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从传统医学到现代医学的黄花蒿素的生物学潜力和治疗效果:药理活性和分析方面的更新。

Biological Potential and Therapeutic Effectiveness of Artemetin from Traditional to Modern Medicine: An Update on Pharmacological Activities and Analytical Aspects.

机构信息

Department of Pharmaceutical Sciences, Sam Higginbottom University of Agriculture, Technology and Sciences, Allahabad, 211007, Uttar Pradesh, India.

出版信息

Recent Adv Antiinfect Drug Discov. 2024;19(4):265-275. doi: 10.2174/0127724344266027231215105620.

Abstract

BACKGROUND

Plant products derived from natural sources have been used in medicine as a raw material and newer kinds of drug molecules in pharmaceuticals and other allied health sectors. Phytochemicals have numerous medicinal potentials, including anti- ageing, anti-carcinogenic, anti-microbial, anti-oxidant, and anti-inflammatory activity in medicine. Development and biological application of herbal products in modern medicine signified the value of traditional medicinal plants in health care systems.

METHODS

The objective of the present study was to explore the scientific knowledge of the medicinal importance and therapeutic potential of artemetin in medicine. However, scientific investigations for their pharmacological activities in medicine have been done through scientific data analysis of different scientific research work collected from PubMed, Google, Science Direct and Google Scholar in order to know the biological importance of artemetin in medicine. Moreover, analytical data of artemetin have also been discussed in the present work.

RESULTS

The present work scientific data signified the biological potential of artemetin in medicine. Artemetin has been derived from numerous medicinal plants and dietary herbs, including . Artemetin has anti-malarial, anti-oxidant, anti-apoptotic, anti-microbial, anti-tumoral, antiatherosclerotic, anti-inflammatory, hypotensive and hepatoprotective effects. Further, the biological role of artemetin on lipid oxidation, cytokine production, lipoxygenase, and estrogen- like effects was also investigated in the present work. Analytical data on artemetin in the present paper signified their important role in the isolation, separation, and identification of different classes of pure phytochemicals, including artemetin in medicine.

CONCLUSION

Scientific data analysis of artemetin signified its therapeutic potential in medicine for the development of newer scientific approaches for different human disorders.

摘要

背景

植物产品源自天然资源,被广泛应用于医学领域,作为医药和其他相关健康领域的新药分子的原料。植物化学物质具有多种药用潜力,包括抗衰老、抗癌、抗菌、抗氧化和抗炎活性。草药产品在现代医学中的开发和生物应用凸显了传统药用植物在医疗保健系统中的价值。

方法

本研究的目的是探索青蒿素在医学中的药用重要性和治疗潜力的科学知识。然而,通过对从 PubMed、Google、Science Direct 和 Google Scholar 收集的不同科学研究工作的科学数据分析,已经对其在医学中的药理学活性进行了科学研究,以了解青蒿素在医学中的生物学重要性。此外,本工作还讨论了青蒿素的分析数据。

结果

本工作的科学数据表明了青蒿素在医学中的生物学潜力。青蒿素来源于多种药用植物和膳食草药,包括黄花蒿。青蒿素具有抗疟疾、抗氧化、抗细胞凋亡、抗菌、抗肿瘤、抗动脉粥样硬化、抗炎、降压和保肝作用。此外,本工作还研究了青蒿素对脂质氧化、细胞因子产生、脂氧合酶和类雌激素作用的生物学作用。本文中关于青蒿素的分析数据表明,它们在不同类别的纯植物化学物质(包括青蒿素)的分离、分离和鉴定中具有重要作用。

结论

青蒿素的科学数据分析表明,它在医学中有治疗潜力,可为开发针对不同人类疾病的新科学方法提供依据。

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