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放疗后罕见且危及生命的髂静脉支架感染:一例强调临床紧迫性和术前支架评估的病例报告

Rare and life-threatening iliac vein stent infection following radiotherapy: a case report emphasizing clinical urgency and preoperative stent evaluation.

作者信息

Liao Jianyu, Ma YuKui, Wu Zhoupeng, Wang Xinyan, Zhao Jichun

机构信息

Division of Vascular Surgery, Department of General Surgery, West China Hospital, Sichuan University, Chengdu, China.

出版信息

Front Cardiovasc Med. 2025 Apr 28;12:1532300. doi: 10.3389/fcvm.2025.1532300. eCollection 2025.

DOI:10.3389/fcvm.2025.1532300
PMID:40357435
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12066436/
Abstract

This case report discussed a 43-year-old female who underwent multiple radiotherapy sessions after cervical cancer surgery and experienced serious complications due to simultaneous iliac vein stent placement immediately after thrombus aspiration without adequate evaluation of the indication for stent placement. Two months after radiotherapy, the patient developed right lower limb edema and pain, which led to the discovery of an iliac vein thrombosis. Subsequent stent placement without thorough evaluation resulted in severe complications, including infection and sepsis. Despite initial symptom relief, the patient was readmitted with high fever and severe pain, and imaging revealed gas around the stent, indicating infection. An exploratory laparotomy uncovered a large abscess and a colonic fistula. The stents were removed, and the patient underwent aggressive anti-infection treatment involving meropenem and vancomycin, along with surgical repair of the fistula. This case highlights the importance of accurate diagnosis and careful consideration of stent placement in preventing severe outcomes, including the rare but serious risk of venous stent infections requiring surgical intervention.

摘要

本病例报告讨论了一名43岁女性,她在宫颈癌手术后接受了多次放疗,并在血栓抽吸后立即同时放置髂静脉支架,而未对支架置入指征进行充分评估,从而出现了严重并发症。放疗两个月后,患者出现右下肢水肿和疼痛,随后发现髂静脉血栓形成。随后未经全面评估就进行支架置入导致了严重并发症,包括感染和脓毒症。尽管最初症状有所缓解,但患者因高热和剧痛再次入院,影像学检查显示支架周围有气体,提示感染。剖腹探查发现一个大脓肿和一个结肠瘘。取出支架后,患者接受了美罗培南和万古霉素的积极抗感染治疗,并进行了瘘管手术修复。本病例强调了准确诊断和谨慎考虑支架置入在预防严重后果中的重要性,包括罕见但严重的静脉支架感染风险,这种感染需要手术干预。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8951/12066436/d27c4b779434/fcvm-12-1532300-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8951/12066436/e8f5bc9bbc4a/fcvm-12-1532300-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8951/12066436/d27c4b779434/fcvm-12-1532300-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8951/12066436/e8f5bc9bbc4a/fcvm-12-1532300-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8951/12066436/d27c4b779434/fcvm-12-1532300-g002.jpg

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本文引用的文献

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Editor's Choice - European Society for Vascular Surgery (ESVS) 2022 Clinical Practice Guidelines on the Management of Chronic Venous Disease of the Lower Limbs.编辑推荐——欧洲血管外科学会(ESVS)2022年下肢慢性静脉疾病管理临床实践指南
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May-Thurner syndrome: History of understanding and need for defining population prevalence.
梅-图二氏综合征:认识历程与界定人群患病率的必要性
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Venous Thromboembolism in Gynecological Malignancy.妇科恶性肿瘤中的静脉血栓栓塞症
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Aortoiliac stent graft infection: current problems and management.主髂动脉支架移植物感染:当前问题与处理
Ann Vasc Surg. 2004 Sep;18(5):521-6. doi: 10.1007/s10016-004-0075-9. Epub 2004 Aug 6.
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The hypercoagulable state of malignancy: pathogenesis and current debate.恶性肿瘤的高凝状态:发病机制与当前争论
Neoplasia. 2002 Nov-Dec;4(6):465-73. doi: 10.1038/sj.neo.7900263.
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The clinical course of deep vein thrombosis in patients with gynecologic cancer.妇科癌症患者深静脉血栓形成的临床病程。
Gynecol Oncol. 2002 Jan;84(1):67-71. doi: 10.1006/gyno.2001.6452.
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