[乳酸对心肌匀浆葡萄糖和琥珀酸氧化效能的影响]
[Effect of lactate on the effectiveness of glucose and succinate oxidation by myocardium homogenates].
作者信息
Ovchinnikov I V, Kim N P
出版信息
Ukr Biokhim Zh (1978). 1985 Jul-Aug;57(4):72-5.
PMID:4035799
Abstract
Lactate (20 mM) was studied for its effect on the intensity of [1-6-14C] glucose and [1,4-14C] succinate oxidation by the rat myocardial homogenates. It is established that lactate induces specific suppression of aerobic glucose oxidation. A moderate reduction of the succinate and lactate oxidation in their combined incubation is of a non-specific character.
摘要
研究了乳酸（20 mM）对大鼠心肌匀浆中[1-6-14C]葡萄糖和[1,4-14C]琥珀酸氧化强度的影响。已证实乳酸可特异性抑制需氧葡萄糖氧化。在它们共同孵育时，琥珀酸和乳酸氧化的适度降低具有非特异性特征。
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