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[乳酸对心肌匀浆葡萄糖和琥珀酸氧化效能的影响]

[Effect of lactate on the effectiveness of glucose and succinate oxidation by myocardium homogenates].

作者信息

Ovchinnikov I V, Kim N P

出版信息

Ukr Biokhim Zh (1978). 1985 Jul-Aug;57(4):72-5.

PMID:4035799
Abstract

Lactate (20 mM) was studied for its effect on the intensity of [1-6-14C] glucose and [1,4-14C] succinate oxidation by the rat myocardial homogenates. It is established that lactate induces specific suppression of aerobic glucose oxidation. A moderate reduction of the succinate and lactate oxidation in their combined incubation is of a non-specific character.

摘要

研究了乳酸(20 mM)对大鼠心肌匀浆中[1-6-14C]葡萄糖和[1,4-14C]琥珀酸氧化强度的影响。已证实乳酸可特异性抑制需氧葡萄糖氧化。在它们共同孵育时,琥珀酸和乳酸氧化的适度降低具有非特异性特征。

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