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基于ICU活动量表在24小时内对癌症患者进行活动干预的效果:一项随机对照临床试验“基于ICU活动量表的活动干预”

Effects of Mobilization Within 24 Hours Based on the ICU Mobility Scale in Cancer Patients: A Randomized Controlled Clinical Trial "Mobilization Based on the ICU Mobility Scale".

作者信息

Silva Flaviana Santos de Sousa, Lima Giérisson Brenno Borges, Lima Gabriel Santos de Castro E, Torres Denise Carvalho, Macedo Michel Monteiro, Amorim Carlos Eduardo Neves

机构信息

Federal University of Maranhão (UFMA), Sao Luís, Brazil.

University Center UniRedentor (UniRedentor), Itaperuna, Brazil.

出版信息

J Surg Oncol. 2025 Jun;131(8):1583-1590. doi: 10.1002/jso.28142. Epub 2025 May 13.

DOI:10.1002/jso.28142
PMID:40358360
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12232096/
Abstract

BACKGROUND AND OBJECTIVE

Abdominal cancer surgery leads to loss of functional capacity. The objective was to evaluate the effects of mobilization within 24 h applied to patients with abdominal neoplasms undergoing major surgery.

METHODS

A randomized controlled clinical trial was carried out in the Intensive Care Unit. The intervention group performed mobility activities guided by the ICU mobility scale (IMS) in the first 24 h after surgery and the control group performed conventional physiotherapy. Dynamometry was evaluated in the preoperative, 1st POD and postoperative period, as well as the Timed up and go test (TUG).

RESULTS

Patients in the intervention group had greater initial mobility (IMS Scale intervention group: 6.67 ± 0.69; IMS Scale control group: 2.23 ± 0.52; p = 0.001). There was greater level of mobility until discharge from the ICU in patients in the intervention group compared to the control group (IMS at discharge from the ICU in the intervention group: 8.53 ± 0.33; IMS at discharge from the ICU in the control group: 3 ± 0.64). Both groups showed worsening in the TUG test, but it was significant only in the control group.

CONCLUSION

Early mobilization in patients with abdominal neoplasms undergoing major surgery proved to be effective in maintaining mobility and functional markers.

摘要

背景与目的

腹部癌症手术会导致功能能力丧失。目的是评估对接受大手术的腹部肿瘤患者在24小时内进行活动干预的效果。

方法

在重症监护病房进行一项随机对照临床试验。干预组在术后头24小时内按照重症监护病房活动量表(IMS)进行活动,对照组进行传统物理治疗。在术前、术后第1天和术后阶段评估握力,以及计时起立行走测试(TUG)。

结果

干预组患者初始活动能力更强(IMS量表干预组:6.67±0.69;IMS量表对照组:2.23±0.52;p = 0.001)。与对照组相比,干预组患者在从重症监护病房出院前的活动水平更高(干预组从重症监护病房出院时的IMS:8.53±0.33;对照组从重症监护病房出院时的IMS:3±0.64)。两组在TUG测试中均显示恶化,但仅在对照组中显著。

结论

对接受大手术的腹部肿瘤患者进行早期活动干预被证明在维持活动能力和功能指标方面是有效的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc50/12232096/d72441fa1bc7/JSO-131-1583-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc50/12232096/c82dc4ddc729/JSO-131-1583-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc50/12232096/d72441fa1bc7/JSO-131-1583-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc50/12232096/c82dc4ddc729/JSO-131-1583-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc50/12232096/d72441fa1bc7/JSO-131-1583-g002.jpg

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本文引用的文献

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BMC Geriatr. 2022 Dec 5;22(1):934. doi: 10.1186/s12877-022-03585-4.
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The Role and Effect of Multimodal Prehabilitation Before Major Abdominal Surgery: A Systemic Review and Meta-Analysis.腹部大手术前多模式预康复的作用及效果:一项系统评价与Meta分析
World J Surg. 2023 Jan;47(1):86-102. doi: 10.1007/s00268-022-06761-0. Epub 2022 Oct 2.
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The effect of mobilization protocol on mobilization start time and patient care outcomes in patients undergoing abdominal surgery.
动员方案对接受腹部手术患者的动员开始时间和患者护理结局的影响。
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Systematic early versus late mobilization or standard early mobilization in mechanically ventilated adult ICU patients: systematic review and meta-analysis.机械通气成人 ICU 患者早期系统活动与晚期活动或标准早期活动的比较:系统评价和荟萃分析。
Crit Care. 2021 Jan 6;25(1):16. doi: 10.1186/s13054-020-03446-9.
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"I Have Everything to Win and Nothing to Lose": Patient Experiences of Mobilization Out of Bed Immediately After Abdominal Surgery.“我有一切可赢,无物可失”:腹部手术后立即离床活动的患者体验。
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Effect of physiotherapy on regaining independent walking in patients with intensive-care-unit-acquired muscle weakness: A cohort study.物理疗法对 ICU 获得性肌无力患者恢复独立行走能力的影响:一项队列研究。
J Rehabil Med. 2019 Oct 29;51(10):797-804. doi: 10.2340/16501977-2606.
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Perioperatively Acquired Weakness.围手术期获得性肌无力。
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[Enhanced recovery after surgery protocol versus conventional perioperative care in colorectal surgery. A single center cohort study].[结直肠手术中术后加速康复方案与传统围手术期护理的比较。一项单中心队列研究]
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Early mobilization programme improves functional capacity after major abdominal cancer surgery: a randomized controlled trial.早期运动方案可改善大型腹部癌症手术后的功能能力:一项随机对照试验。
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