Dale Simon D, Elliott Megan R, Brandolese Arianna, Dove Andrew P, O'Reilly Rachel K
School of Chemistry, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Chemistry. 2025 Jun 23;31(35):e202501290. doi: 10.1002/chem.202501290. Epub 2025 May 24.
Crystallization-driven self-assembly (CDSA) has been extensively studied for the formation of bespoke nanoparticles and provides a unique way to control the unidirectional growth of block copolymers (BCPs). Currently, oil-soluble nanoparticles represent an under-researched area in the literature, stemming from the difficulty in synthesizing organic nanoparticles with higher-order morphologies using traditional techniques. These oil-soluble nanoparticles have uses as components in products as diverse as electronics and engine oils, with current research determining a strong relationship between morphology and performance, with anisotropic nanoparticles outperforming spherical counterparts. Here, we report on the facile self-assembly of polyester-based BCPs in n-octane to achieve low-dispersity 1D and 2D nanoparticles. This report focuses on using tunable, oil-soluble polymers and aims to understand their self-assembly in n-octane through the variation of self-assembly conditions and unimer solubility to form nanoparticles of a controlled and variable size.
结晶驱动自组装（CDSA）已被广泛研究用于定制纳米颗粒的形成，并为控制嵌段共聚物（BCP）的单向生长提供了独特的方法。目前，油溶性纳米颗粒在文献中是一个研究不足的领域，这源于使用传统技术合成具有高阶形态的有机纳米颗粒存在困难。这些油溶性纳米颗粒可作为电子和发动机油等多种产品的成分，目前的研究确定了形态与性能之间的紧密关系，各向异性纳米颗粒的性能优于球形纳米颗粒。在此，我们报道了聚酯基BCP在正辛烷中的简便自组装，以实现低分散性的一维和二维纳米颗粒。本报告重点关注使用可调节的油溶性聚合物，并旨在通过改变自组装条件和单分子溶解度来了解它们在正辛烷中的自组装过程，从而形成尺寸可控且可变的纳米颗粒。
