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利用区域数据仪表盘缩短急性缺血性卒中溶栓时间:来自佛罗里达卒中登记处的结果

Enhancing Thrombolysis Times in Acute Ischemic Stroke With Regional Dashboards: Results From the Florida Stroke Registry.

作者信息

Del Brutto Victor J, Gutierrez Carolina M, Ying Hao, Gardener Hannah, Veledar Emir, Jameson Angus, Scheppke Kenneth A, Rose David Z, Sand Charlie, Antevy Peter, Hylton Tara, Gordon Perue Gillian, Asdaghi Negar, Rundek Tatjana, Mehta Brijesh P, Romano Jose G

机构信息

Department of Neurology University of Miami Miller School of Medicine Miami FL USA.

University of South Florida, Morsani College of Medicine Tampa FL USA.

出版信息

J Am Heart Assoc. 2025 May 20;14(10):e040611. doi: 10.1161/JAHA.124.040611. Epub 2025 May 13.

Abstract

BACKGROUND

Reducing time to intravenous thrombolysis (IVT) is crucial for effective ischemic stroke treatment. Through grassroots efforts, the FSR (Florida Stroke Registry) developed regional dashboards (RDs) displaying reperfusion metrics within local Stroke Coalitions to improve acute stroke care quality. We sought to evaluate whether RD use is associated with faster IVT times and improved hospitalization outcomes.

METHODS

We compared IVT-treated cases of ischemic stroke at FSR hospitals participating in the RD initiative versus nonparticipating hospitals from January 2016 to December 2023. Primary outcomes were door-to-treatment time <20 minutes and onset-to-treatment time <60 minutes. Secondary outcomes included intracerebral hemorrhage after IVT, discharge disposition, and in-hospital death. Logistic regression models, adjusted for calendar year, patient characteristics, and hospital factors, assessed the association between RD use and study outcomes.

RESULTS

By the end of the study period, 92 of 172 FSR hospitals (53.5%) were participating in stroke coalitions and using RDs. Among 32 320 IVT-treated cases (mean age, 69±15 years, 48.4% women), 10 666 (33.0%) were treated in RD-participating hospitals. RD participation was independently associated with door-to-treatment time <20 minutes (12.7% versus 7.3%; adjusted odds ratio, 1.48 [95% CI, 1.35-1.63]) and onset-to-treatment time <60 minutes (13.9% versus 9.0%; adjusted odds ratio, 1.63 [95% CI, 1.49-1.80]), as well as increased likelihood of being discharged directly to home (adjusted odds ratio, 1.15 [95% CI, 1.07-1.23]).

CONCLUSIONS

The implementation of the FSR RD initiative within stroke coalitions was associated with faster IVT times and higher likelihood of home discharge. This quality improvement initiative, adaptable to local needs, could emerge as a valuable tool for enhancing stroke systems of care.

摘要

背景

缩短静脉溶栓(IVT)时间对于缺血性脑卒中的有效治疗至关重要。通过基层努力,佛罗里达州卒中登记处(FSR)开发了区域仪表盘(RDs),用于展示当地卒中联盟内的再灌注指标,以提高急性卒中护理质量。我们旨在评估使用RDs是否与更快的IVT时间及改善的住院结局相关。

方法

我们比较了2016年1月至2023年12月期间参与RD倡议的FSR医院与未参与的医院中接受IVT治疗的缺血性脑卒中病例。主要结局为门到治疗时间<20分钟和发病到治疗时间<60分钟。次要结局包括IVT后脑出血、出院去向和院内死亡。采用经日历年份、患者特征和医院因素调整的逻辑回归模型,评估使用RDs与研究结局之间的关联。

结果

到研究期结束时,172家FSR医院中有92家(53.5%)参与了卒中联盟并使用了RDs。在32320例接受IVT治疗的病例(平均年龄69±15岁,48.4%为女性)中,10666例(33.0%)在参与RD的医院接受治疗。参与RD与门到治疗时间<20分钟(12.7%对7.3%;调整后的优势比,1.48[95%CI,1.35 - 1.63])和发病到治疗时间<60分钟(13.9%对9.0%;调整后的优势比,1.63[95%CI,1.49 - 1.80])独立相关,同时直接出院回家的可能性增加(调整后的优势比,1.15[95%CI,1.07 - 1.23])。

结论

在卒中联盟内实施FSR的RD倡议与更快的IVT时间和更高的出院回家可能性相关。这一质量改进举措可根据当地需求进行调整,可能成为加强卒中护理系统的宝贵工具。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b5e3/12184594/14b178206e25/JAH3-14-e040611-g003.jpg

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