Li Zhiyuan, Yu Chenhang, Chen Huan
GBD Collaborator, Nanjing Stomatological Hospital, Medical School of Nanjing University, 22 Hankou Road, Nanjing, 210093, China.
Wuxi Stomatological Hospital, 6 Jiankang Road, Wuxi, 214000, China.
BMC Oral Health. 2025 May 13;25(1):715. doi: 10.1186/s12903-025-06086-z.
This study aims to analyze the global, regional, and national incidence, prevalence, and disability-adjusted life years (DALYs) related to caries of permanent teeth from 1990 to 2021, as part of the Global Burden of Disease Study (GBD).
Data on incidence, prevalence, and DALYs were extracted and analyzed for various demographic and regional categories. Age-standardized incidence rates (ASIR), age-standardized prevalence rates (ASPR), and age-standardized DALY rates (ASDAR) were calculated. Temporal trends and associations with sociodemographic index (SDI) were also examined.
In 2021, there were approximately 2.37 billion cases of caries of permanent teeth, with an ASIR of 29,777.03 per 100,000 population. The prevalence was around 2.24 billion, with an ASPR of 27,543.34 per 100,000. Females exhibited a higher disease burden than males, and the burden increased with age, peaking in the 20-24 age group. Regions with lower SDI showed higher ASIRs, while the highest burden was noted in Tropical Latin America. Significant increases in disease burden were observed from 1990 to 2021, particularly in China and Colombia, while Japan showed a decrease. The Bayesian age-period-cohort (BAPC) predictions indicate that the burden of caries of permanent teeth will continue to increase year by year.
The burden of caries of permanent teeth varies significantly across regions and demographics, with higher rates in lower SDI areas. The findings underscore the importance of targeted interventions and resource allocation in high-burden regions to improve dental health outcomes.
作为全球疾病负担研究(GBD)的一部分,本研究旨在分析1990年至2021年期间与恒牙龋相关的全球、区域和国家发病率、患病率及伤残调整生命年(DALY)。
提取并分析了不同人口统计学和区域类别的发病率、患病率及DALY数据。计算了年龄标准化发病率(ASIR)、年龄标准化患病率(ASPR)和年龄标准化DALY率(ASDAR)。还研究了时间趋势以及与社会人口指数(SDI)的关联。
2021年,恒牙龋病例约有23.7亿例,ASIR为每10万人29777.03例。患病率约为22.4亿例,ASPR为每10万人27543.34例。女性的疾病负担高于男性,且负担随年龄增加而上升,在20 - 24岁年龄组达到峰值。SDI较低的地区ASIR较高,而热带拉丁美洲的负担最重。1990年至2021年期间观察到疾病负担显著增加,尤其是在中国和哥伦比亚,而日本则有所下降。贝叶斯年龄 - 时期 - 队列(BAPC)预测表明,恒牙龋的负担将逐年持续增加。
恒牙龋的负担在不同地区和人口统计学特征中差异显著,SDI较低的地区发病率较高。研究结果强调了在高负担地区进行有针对性的干预和资源分配以改善口腔健康结果的重要性。