Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, 81 Meishan Road, Hefei, Anhui 230032, China.
School of Public Health, BengBu Medical University, 2600 Donghai Avenue, Bengbu, Anhui 233030, China.
Sci Total Environ. 2024 May 20;926:171739. doi: 10.1016/j.scitotenv.2024.171739. Epub 2024 Mar 19.
Exposure to ambient ozone pollution causes health loss and even death, and both are the main risk factors for the disease burden worldwide. We comprehensively evaluated the ozone pollution-related disease burden.
First, numbers and age-standardized rates of deaths and disability-adjusted life years (DALYs) were assessed globally and by sub-types in 2019. Furthermore, the temporal trend of the disease burden was explored by the linear regression model from 1990 to 2019. The cluster analysis was used to evaluate the changing pattern of related disease burden across Global Burden of Disease Study (GBD) regions. Finally, the age-period-cohort (APC) model and the Bayesian age-period-cohort (BAPC) model were used to predict the future disease burden in the next 25 years.
Exposure to ozone pollution contributed to 365,222 deaths and 6,210,145 DALYs globally in 2019, which accounted for 0.65 % of deaths globally and 0.24 % of DALYs globally. The disease burden was consistently increasing with age. Males were high-risk populations and low-middle socio-demographic index (SDI) regions were high-risk areas. The disease burden of ozone pollution varied considerably across the GBD regions and the countries. In 2019, the number of deaths and DALYs cases increased by 76.11 % and 56.37 %, respectively compared to those in 1990. The predicted results showed that the number of deaths cases and DALYs cases for both genders would still increase from 2020 to 2044.
In conclusion, ambient ozone pollution has threatened public health globally. More proactive and effective strategic measures should be developed after considering global-specific circumstances.
暴露于环境臭氧污染会导致健康损失甚至死亡，这两者都是全球疾病负担的主要风险因素。我们全面评估了臭氧污染相关的疾病负担。
首先，我们评估了 2019 年全球和各亚组的死亡人数和年龄标准化死亡率以及伤残调整生命年（DALY）。此外，我们还通过线性回归模型从 1990 年到 2019 年探讨了疾病负担的时间趋势。聚类分析用于评估全球疾病负担研究（GBD）区域内相关疾病负担的变化模式。最后，我们使用年龄-时期-队列（APC）模型和贝叶斯年龄-时期-队列（BAPC）模型预测未来 25 年的疾病负担。
2019 年，臭氧污染暴露导致全球 365222 人死亡和 6210145 个 DALY，占全球死亡人数的 0.65%和全球 DALY 的 0.24%。疾病负担随着年龄的增长而持续增加。男性是高风险人群，中低社会人口指数（SDI）地区是高风险地区。臭氧污染的疾病负担在 GBD 区域和国家之间差异很大。2019 年，与 1990 年相比，死亡人数和 DALY 病例数分别增加了 76.11%和 56.37%。预测结果表明，从 2020 年到 2044 年，男女两性的死亡人数和 DALY 病例数仍将继续增加。
总之，环境臭氧污染已经对全球公共健康构成威胁。在考虑全球具体情况后，应制定更积极和有效的战略措施。
