Lack of congruence of S-carboxymethyl-L-cysteine sulphoxidation and debrisoquine 4-hydroxylation in a Caucasian population.
作者信息
Haley C S, Waring R H, Mitchell S C, Shah R R, Idle J R, Smith R L
出版信息
Xenobiotica. 1985 May;15(5):445-50. doi: 10.3109/00498258509045015.
PMID:4036168
Abstract
One-hundred-and-twenty volunteers and three families were investigated for possible association between the sulphoxidation of S-carboxymethyl-L-cysteine and the debrisoquine hydroxylation polymorphism. The observed individual variations in these two metabolic reactions were shown not to be concordant (rs = 0.068) and any heritable factors controlling the major aspects of these phenomena do not co-segregate.
摘要
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