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Lack of defect in oxidative hydroxylation of debrisoquine in a patient with halothane hepatitis.

作者信息

Toutoungi M, Magnenat D

机构信息

Department of Clinical Psychopharmacology, University of Geneva, Chene Bourg, Switzerland.

出版信息

Eur J Clin Pharmacol. 1990;38(6):633-4. doi: 10.1007/BF00278596.

DOI:10.1007/BF00278596
PMID:2373140
Abstract
摘要

相似文献

1
Lack of defect in oxidative hydroxylation of debrisoquine in a patient with halothane hepatitis.氟烷性肝炎患者中去甲丙咪嗪氧化羟基化无缺陷。
Eur J Clin Pharmacol. 1990;38(6):633-4. doi: 10.1007/BF00278596.
2
The influence of cimetidine on debrisoquine 4-hydroxylation in extensive metabolizers.西咪替丁对快代谢者中异喹胍4-羟化作用的影响。
Eur J Clin Pharmacol. 1989;36(3):319-21. doi: 10.1007/BF00558167.
3
Lack of congruence of S-carboxymethyl-L-cysteine sulphoxidation and debrisoquine 4-hydroxylation in a Caucasian population.
Xenobiotica. 1985 May;15(5):445-50. doi: 10.3109/00498258509045015.
4
In vitro evidence against the oxidation of quinidine by the sparteine/debrisoquine monooxygenase of human liver.关于人肝脏中司巴丁/异喹胍单加氧酶对奎尼丁氧化作用的体外证据。
Drug Metab Dispos. 1988 Jan-Feb;16(1):15-7.
5
Stereoselective 4-hydroxylation of debrisoquine in Nigerians.
Biochem Pharmacol. 1988 Jan 1;37(1):97-8. doi: 10.1016/0006-2952(88)90759-9.
6
Is debrisoquine hydroxylation modified during acute viral hepatitis?在急性病毒性肝炎期间，异喹胍羟基化是否会发生改变？
Fundam Clin Pharmacol. 1994;8(1):76-9. doi: 10.1111/j.1472-8206.1994.tb00782.x.
7
A human cytochrome P-450 characterized by inhibition studies as the sparteine-debrisoquine monooxygenase.一种通过抑制研究鉴定为司巴丁-异喹胍单加氧酶的人细胞色素P-450。
Can J Physiol Pharmacol. 1984 Jul;62(7):860-2. doi: 10.1139/y84-144.
8
Substrate specificity of the form of cytochrome P-450 catalyzing the 4-hydroxylation of debrisoquine in man.人肝脏中催化异喹胍4-羟化反应的细胞色素P-450形式的底物特异性
Mol Pharmacol. 1983 Mar;23(2):474-81.
9
Quinidine and the identification of drugs whose elimination is impaired in subjects classified as poor metabolizers of debrisoquine.奎尼丁以及对那些被归类为异喹胍代谢缓慢者体内消除受损药物的鉴定。
Br J Clin Pharmacol. 1986 Dec;22(6):739-43. doi: 10.1111/j.1365-2125.1986.tb02969.x.
10
Characterization of a human liver cytochrome P-450 involved in the oxidation of debrisoquine and other drugs by using antibodies raised to the analogous rat enzyme.通过使用针对类似大鼠酶产生的抗体来鉴定参与异喹胍和其他药物氧化的人肝脏细胞色素P-450。
Proc Natl Acad Sci U S A. 1984 Dec;81(23):7348-52. doi: 10.1073/pnas.81.23.7348.

本文引用的文献

1
Influence of DH/DL alleles regulating debrisoquine oxidation on phenytoin hydroxylation.调控异喹胍氧化的DH/DL等位基因对苯妥英羟化作用的影响。
Clin Pharmacol Ther. 1981 Apr;29(4):493-7. doi: 10.1038/clpt.1981.68.
2
Pharmacogenetics of mephenytoin: a new drug hydroxylation polymorphism in man.美芬妥英的药物遗传学：人类一种新的药物羟基化多态性
Eur J Clin Pharmacol. 1984;26(6):753-9. doi: 10.1007/BF00541938.
3
Halothane anaesthesia and liver damage.氟烷麻醉与肝损伤。
Br Med J (Clin Res Ed). 1984 Oct 27;289(6452):1136-9. doi: 10.1136/bmj.289.6452.1136.
4
Halothane hepatitis. Detection of a constitutional susceptibility factor.氟烷性肝炎。一种体质易感性因素的检测。
N Engl J Med. 1985 Nov 21;313(21):1310-4. doi: 10.1056/NEJM198511213132102.
5
Mephenytoin hydroxylation polymorphism: characterization of the enzymatic deficiency in liver microsomes of poor metabolizers phenotyped in vivo.
Clin Pharmacol Ther. 1985 Nov;38(5):488-94. doi: 10.1038/clpt.1985.213.
6
The debrisoquin hydroxylation phenotype does not predict the metabolism of phenytoin.异喹胍羟基化表型不能预测苯妥英的代谢。
Clin Pharmacol Ther. 1987 Sep;42(3):326-33. doi: 10.1038/clpt.1987.156.
7
Propranolol's metabolism is determined by both mephenytoin and debrisoquin hydroxylase activities.
Clin Pharmacol Ther. 1989 Jan;45(1):72-9. doi: 10.1038/clpt.1989.11.
8
Dextromethorphan O-demethylation in liver microsomes as a prototype reaction to monitor cytochrome P-450 db1 activity.肝脏微粒体中右美沙芬O-去甲基化作为监测细胞色素P-450 db1活性的原型反应。
Clin Pharmacol Ther. 1989 Jan;45(1):34-40. doi: 10.1038/clpt.1989.6.
9
Polymorphism of cytochrome P-450 in humans.人类细胞色素P-450的多态性。
Trends Pharmacol Sci. 1989 Mar;10(3):107-9. doi: 10.1016/0165-6147(89)90207-1.
10
Polymorphism of carbon oxidation of drugs and clinical implications.药物碳氧化的多态性及其临床意义。
Br Med J. 1978 Sep 2;2(6138):655-7. doi: 10.1136/bmj.2.6138.655.