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儿童炎症性肠病中的微量营养素缺乏:发生率、原因及应对措施?

Micronutrient Deficiencies in Pediatric IBD: How Often, Why, and What to Do?

作者信息

Galeazzi Tiziana, Quattrini Sara, Lionetti Elena, Gatti Simona

机构信息

Department of Pediatrics, Polytechnic University of Marche, 60123 Ancona, Italy.

出版信息

Nutrients. 2025 Apr 24;17(9):1425. doi: 10.3390/nu17091425.

Abstract

Inflammatory bowel disease (IBDs), including Crohn's disease (CD), and ulcerative colitis (UC) are complex diseases with a multifactorial etiology, associated with genetic, dietetic, and other environmental risk factors. Children with IBD are at increased risk for nutritional inadequacies, resulting from decreased oral intake, restrictive dietary patterns, malabsorption, enhanced nutrient loss, surgery, and medications. Follow-up of IBD children should routinely include evaluation of specific nutritional deficits and dietetic and/or supplementation strategies should be implemented in case deficiencies are detected. This narrative review focuses on the prevalence, risk factors, detection strategy, and management of micronutrient deficiencies in pediatric IBD.

摘要

炎症性肠病(IBD),包括克罗恩病(CD)和溃疡性结肠炎(UC),是病因多因素的复杂疾病,与遗传、饮食及其他环境风险因素相关。患有IBD的儿童出现营养不足的风险增加,这是由口服摄入量减少、限制性饮食模式、吸收不良、营养流失增加、手术及药物治疗所致。对IBD儿童的随访应常规包括对特定营养缺乏情况的评估,一旦发现缺乏情况,应实施饮食和/或补充策略。本叙述性综述重点关注儿科IBD中微量营养素缺乏的患病率、风险因素、检测策略及管理。

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