Jarmakiewicz-Czaja Sara, Ferenc Katarzyna, Sokal-Dembowska Aneta, Filip Rafał
Institute of Health Sciences, Medical College of Rzeszow University, 35-959 Rzeszow, Poland.
Institute of Medicine, Medical College of Rzeszow University, 35-959 Rzeszow, Poland.
Int J Mol Sci. 2024 Apr 16;25(8):4390. doi: 10.3390/ijms25084390.
The problem of treating inflammatory bowel disease continues to be a topic of great interest for researchers. Despite the complexity surrounding their treatment and strategies to prolong periods of remission, there is a promising exploration of various compounds that have potential in combating inflammation and alleviating symptoms. Selenium, calcium, magnesium, zinc, and iron are among these compounds, offering a glimpse of hope in the treatment of IBD. These essential minerals not only hold the promise of reducing inflammation in these diseases, but also show the potential to enhance immune function and possibly influence the balance of intestinal microflora. By potentially modulating the gut microbiota, they may help support overall immune health. Furthermore, these compounds could play a crucial role in mitigating inflammation and minimising complications in patients with IBD. Furthermore, the protective effect of these compounds against mucosal damage in IBD and the protective effect of calcium itself against osteoporosis in this group of patients are notable.
治疗炎症性肠病的问题仍然是研究人员非常感兴趣的话题。尽管其治疗以及延长缓解期的策略很复杂,但对于各种具有抗炎和缓解症状潜力的化合物仍有充满前景的探索。硒、钙、镁、锌和铁都属于这些化合物,为炎症性肠病的治疗带来了一线希望。这些必需矿物质不仅有望减轻这些疾病中的炎症,还显示出增强免疫功能以及可能影响肠道微生物群平衡的潜力。通过潜在地调节肠道微生物群,它们可能有助于支持整体免疫健康。此外,这些化合物在减轻炎症性肠病患者的炎症和减少并发症方面可能发挥关键作用。此外,这些化合物对炎症性肠病黏膜损伤的保护作用以及钙本身对该组患者骨质疏松症的保护作用值得注意。