Mulyani Aisyah Tri, Khairinisa Miski Aghnia, Khatib Alfi, Chaerunisaa Anis Yohana
Magister Program, Faculty of Pharmacy, University of Padjadjaran, Jalan Raya Bandung Sumedang km 21 Jatinangor, Sumedang 45363, Indonesia.
Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, University of Padjadjaran, Jalan Raya Bandung Sumedang km 21 Jatinangor, Sumedang 45363, Indonesia.
Nutrients. 2025 Apr 29;17(9):1493. doi: 10.3390/nu17091493.
Stunting is a major global health concern, particularly in low- and middle-income countries, due to its persistently high prevalence. It often originates from chronic malnutrition during the critical first 1000 days of life. Maternal and child nutrition are critical determinants of a child's growth and development. This article aimed to explore the impact, causes, and evidence-based strategies to accelerate the reduction of stunting incidence worldwide. This review was undertaken with sources from PubMed, Scopus, Google Scholar, Science Direct, and MEDLINE from October 2024 to January 2025. This review was undertaken with sources from PubMed, Scopus, Google Scholar, Science Direct, and MEDLINE from October 2024 to January 2025 using the keyword "Stunting", "Causes of stunting", "Stunting Impact", "Stunting Intervention", and "Stunting Prevention". The findings highlight the multifactorial causes of stunting, including maternal malnutrition, inadequate breastfeeding and complementary feeding, poor sanitation, and socioeconomic factors. Stunting is associated with impaired linear growth, cognitive deficits, gut dysbiosis, endocrine disruption, anemia, and increased risk of chronic diseases later in life. Addressing stunting demands multisectoral strategies focusing on maternal and child nutrition, infection prevention, improved WASH (Water, Sanitation, and Hygiene) practices, and socioeconomic support. The evidence presented may guide policy development and targeted interventions to prevent stunting and its long-term effects.
发育迟缓是一个重大的全球健康问题,尤其是在低收入和中等收入国家,因为其患病率一直居高不下。它通常源于生命最初1000天的慢性营养不良。母婴营养是儿童生长发育的关键决定因素。本文旨在探讨加速全球发育迟缓发病率降低的影响、原因和循证策略。本综述于2024年10月至2025年1月期间,从PubMed、Scopus、谷歌学术、科学Direct和MEDLINE获取资料。本综述于2024年10月至2025年1月期间,从PubMed、Scopus、谷歌学术、科学Direct和MEDLINE获取资料,使用关键词“发育迟缓”、“发育迟缓的原因”、“发育迟缓的影响”、“发育迟缓的干预”和“发育迟缓的预防”。研究结果突出了发育迟缓的多因素成因,包括母亲营养不良、母乳喂养和辅食添加不足、卫生条件差以及社会经济因素。发育迟缓与线性生长受损、认知缺陷、肠道菌群失调、内分泌紊乱、贫血以及晚年患慢性病的风险增加有关。解决发育迟缓问题需要多部门策略,重点关注母婴营养、感染预防、改善水、环境卫生和个人卫生(WASH)措施以及社会经济支持。所提供的证据可为政策制定和针对性干预提供指导,以预防发育迟缓及其长期影响。