Kim Minsang, Koh Jung Hun, Cho Jeong Min, Cho Semin, Lee Soojin, Huh Hyuk, Kim Seong Geun, Jung Sehyun, Kang Eunjeong, Park Sehoon, Paek Jin Hyuk, Park Woo Yeong, Jin Kyubok, Han Seungyeup, Joo Kwon Wook, Han Kyungdo, Kim Dong Ki, Kim Yaerim
Department of Internal Medicine, Seoul National University Hospital, Seoul 03080, Republic of Korea.
Department of Internal Medicine, Chung-Ang University Gwangmyeong Hospital, Gwangmyeong 14353, Republic of Korea.
Nutrients. 2025 May 7;17(9):1600. doi: 10.3390/nu17091600.
: Although a healthy dietary pattern is a modifiable lifestyle factor in the prevention of chronic kidney disease (CKD), studies that investigate the association between a healthy diet and prevalent CKD in patients with diabetes, using the Korean Healthy Eating Index (KHEI), are lacking. : This cross-sectional study included 1991 patients with diabetes from the eighth Korean National Health and Nutrition Examination Survey 2019-2021. A higher KHEI indicated healthier eating habits. CKD was defined as an estimated glomerular filtration rate < 60 mL/min/1.73 m or urine albumin-creatinine ratio ≥ 30 mg/g. The risk of prevalent CKD was evaluated according to the median KHEI value using logistic regression analysis adjusted for various clinicodemographic characteristics. Each KHEI component score was compared between those with and those without CKD, using the Student's -test. : Participants with a higher KHEI were older, with higher proportions of women, non-smokers, and non-alcoholics. A higher KHEI was significantly associated with a lower risk of prevalent CKD (adjusted odds ratio [aOR], 0.73 [0.58-0.93]). Subgroup analysis revealed stronger associations in those without hypertension status (aOR, 0.57 [0.37-0.87]) with at least high school education (aOR, 0.56 [0.38-0.81]). Moreover, patients with diabetes and CKD had significantly lower KHEI, particularly in the adequacy category components, including breakfast consumption, total fruit intake, and dairy product intake. : A healthier dietary pattern was associated with a lower risk of prevalent CKD in patients with diabetes. Dietary intervention, which recommends the intake of breakfast, fruits, and dairy products, may be an effective strategy for CKD prevention.
尽管健康的饮食模式是预防慢性肾脏病(CKD)中一种可改变的生活方式因素,但利用韩国健康饮食指数(KHEI)来研究健康饮食与糖尿病患者中CKD患病率之间关联的研究却很缺乏。 这项横断面研究纳入了2019 - 2021年第八次韩国全国健康与营养检查调查中的1991名糖尿病患者。较高的KHEI表明饮食习惯更健康。CKD被定义为估计肾小球滤过率<60 mL/min/1.73 m²或尿白蛋白 - 肌酐比值≥30 mg/g。使用针对各种临床人口统计学特征进行调整的逻辑回归分析,根据KHEI中位数评估CKD患病率的风险。使用学生t检验比较有CKD和无CKD患者之间的每个KHEI成分得分。 KHEI较高的参与者年龄较大,女性、非吸烟者和不饮酒者的比例更高。较高的KHEI与较低的CKD患病率风险显著相关(调整后的优势比[aOR],0.73[0.58 - 0.93])。亚组分析显示,在无高血压状态的人群中关联更强(aOR,0.57[0.37 - 0.87]),以及至少接受过高中教育的人群中(aOR,0.56[0.38 - 0.81])。此外,患有糖尿病和CKD的患者KHEI显著较低,特别是在充足性类别成分方面,包括早餐摄入量、水果总摄入量和乳制品摄入量。 更健康的饮食模式与糖尿病患者较低的CKD患病率风险相关。建议摄入早餐、水果和乳制品的饮食干预可能是预防CKD的有效策略。