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三种不同聚合物基直接修复材料的机械、抗菌和物理化学性能:一项体外研究

Mechanical, Antibacterial, and Physico-Chemical Properties of Three Different Polymer-Based Direct Restorative Materials: An In Vitro Study.

作者信息

Laporte Chloé, Bourgi Rim, Jmal Hamdi, Ben Ammar Teissir, Hazko Sandy, Addiego Frédéric, Sauro Salvatore, Haïkel Youssef, Kharouf Naji

机构信息

Department of Biomaterials and Bioengineering, INSERM UMR_S 1121, University of Strasbourg, 67000 Strasbourg, France.

Department of Endodontics and Conservative Dentistry, Faculty of Dental Medicine, University of Strasbourg, 67000 Strasbourg, France.

出版信息

Polymers (Basel). 2025 May 6;17(9):1272. doi: 10.3390/polym17091272.

Abstract

A novel resin-based bulk-fill restorative material (ST; Stela SDI, Bayswater, Victoria, Australia) has been recently introduced as a self-curing alternative to traditional light-cured composites. Promoted for its unlimited depth of cure, enhanced aesthetics, and unique primer composition, it aims to address challenges associated with amalgam and light-curing composites. Thus, the aim of this in vitro study was to investigate the performance of the new self-curing polymer-based restorative material, ST, compared to two conventional light-cured composites for direct restoration. The study evaluated compressive strength with and without aging, antibacterial activity, mineral deposition in contact with Phosphate-Buffered Saline (PBS) and artificial saliva, porosity, and wettability of ST (Tetric EvoCeram (TE; Ivoclar Vivadent, Schaan, Liechtenstein) and Clearfil Majesty ES-2 (CM; Kuraray Noritake Dental, Tokyo, Japan)). The data was statistically analyzed (α = 0.05) through one-way and two-way analysis of variance (ANOVA). ST demonstrated significantly higher compressive strength than TE and CM at baseline and after aging ( < 0.001), while aging significantly reduced compressive strength across all materials ( < 0.001). Fracture mode analysis revealed brittle fractures for TE and CM, whereas ST fractured in multiple smaller fragments. CM showed the highest void volume and diameter, significantly differing from ST and TE ( < 0.001). Scanning electron microscopy (SEM) analysis revealed cubical-like crystalline formations on ST's surface after 28 days of immersion in PBS and saliva, indicating some level of bioactivity, whereas no changes were observed for TE and CM. Wettability testing showed ST had the lowest contact angle (12.24° ± 2.1°) compared to TE (62.78° ± 4.68°) and CM (64.64° ± 3.72°) ( < 0.001). Antibacterial activity testing displayed a significant decrease in bacterial growth for CM compared to ST ( = 0.001) and TE ( = 0.002); however, ST and TE showed no significant differences ( = 0.950). To conclude, ST Automix demonstrated promising results across several key parameters, making it a potential candidate for long-lasting restorative applications. Future studies should explore its long-term clinical performance and investigate formulations that enhance its antibacterial properties. Moreover, the bond strength of these materials to dentin and the cytotoxicity should be evaluated.

摘要

一种新型的树脂基大块充填修复材料(ST;Stela SDI,澳大利亚维多利亚州贝斯沃特)最近被推出,作为传统光固化复合材料的自固化替代品。因其无限的固化深度、增强的美观性和独特的底漆成分而受到推广,旨在解决与汞合金和光固化复合材料相关的挑战。因此,本体外研究的目的是研究新型自固化聚合物基修复材料ST与两种用于直接修复的传统光固化复合材料相比的性能。该研究评估了ST(Tetric EvoCeram(TE;义获嘉伟瓦登特,列支敦士登沙恩)和Clearfil Majesty ES - 2(CM;可乐丽诺瑞特牙科,日本东京))在有无老化情况下的抗压强度、抗菌活性、与磷酸盐缓冲盐水(PBS)和人工唾液接触时的矿物质沉积、孔隙率和润湿性。通过单向和双向方差分析(ANOVA)对数据进行统计学分析(α = 0.05)。在基线和老化后,ST的抗压强度显著高于TE和CM(<0.001),而老化显著降低了所有材料的抗压强度(<0.001)。断裂模式分析显示TE和CM为脆性断裂,而ST断裂成多个较小碎片。CM显示出最高的孔隙体积和直径,与ST和TE有显著差异(<0.001)。扫描电子显微镜(SEM)分析显示,在PBS和唾液中浸泡28天后,ST表面有立方体状晶体形成,表明有一定程度的生物活性,而TE和CM未观察到变化。润湿性测试表明,与TE(62.78°±4.68°)和CM(64.64°±3.72°)相比,ST的接触角最低(12.24°±2.1°)(<0.001)。抗菌活性测试显示,与ST(P = 0.001)和TE(P = 0.002)相比,CM的细菌生长显著减少;然而,ST和TE之间没有显著差异(P = 0.950)。总之,ST自动混合材料在几个关键参数上显示出有前景的结果,使其成为长期修复应用的潜在候选材料。未来的研究应探索其长期临床性能,并研究增强其抗菌性能的配方。此外,应评估这些材料与牙本质的粘结强度和细胞毒性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e40/12073671/26cf2ac7833e/polymers-17-01272-g001.jpg

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