Sądel Michał, Grzanka Leszek, Swakoń Jan, Wróbel Damian, Kusyk Sebastian, Bossin Lily, Bilski Paweł
Institute of Nuclear Physics Polish Academy of Sciences, PL-31342 Krakow, Poland.
Department of Radiation Safety and Security, Paul Scherrer Institute, Forschungsstrasse 111, 5232 Villigen, Switzerland.
Materials (Basel). 2025 Apr 24;18(9):1928. doi: 10.3390/ma18091928.
A novel reusable silicon foil dosimeter based on the new emerging optically stimulated luminescence (OSL) material MgBO:Ce,Li (MBO) is developed and characterized for dosimetric verification of spatially resolved radiotherapy doses. Direct comparison of the spatial (two-2D towards three-3D) proton dose mapping can be achieved with an appropriately designed optical detection setup equipped with a light source (e.g., LEDs) that illuminates the dosimeter and a highly sensitive CCD camera that simultaneously acquires the 2D OSL light from the foil. The newly designed (2nd generation) optical setup allows the registration of high-resolution 2D proton doses (below 0.1 mm resolution) and reconstruction of the 2D proton dose distribution with an accuracy comparable to that of the Gafchromic foils, the current standard of passive 2D dosimetry in radiotherapy. This article outlines the technology's potential application with respect to the commercially available Gafchromic EBT3 films in measurements of the clinically relevant, spatial proton dose mapping. The obtained comparison of the proton radial dose profiles (for EBT3 films vs MBO foils) agrees within 5%. The resulting image resolution (0.074 mm/px for MBO foil) corresponded well with the tested EBT3 films (0.085 mm/px), indicating excellent properties for future 3D proton dose verifications of modern radiotherapy techniques (e.g., proton radiotherapy).
基于新出现的光激发发光（OSL）材料MgBO:Ce,Li（MBO），开发了一种新型可重复使用的硅箔剂量计，并对其进行了表征，用于空间分辨放射治疗剂量的剂量验证。通过配备光源（如发光二极管）以照射剂量计的适当设计的光学检测装置和同时从箔片获取二维OSL光的高灵敏度电荷耦合器件（CCD）相机，可以实现空间（二维到三维）质子剂量映射的直接比较。新设计的（第二代）光学装置能够记录高分辨率二维质子剂量（分辨率低于0.1毫米），并重建二维质子剂量分布，其精度与Gafchromic箔相当，Gafchromic箔是放射治疗中被动二维剂量测定的当前标准。本文概述了该技术在临床上相关的空间质子剂量映射测量中相对于市售Gafchromic EBT3薄膜的潜在应用。所获得的质子径向剂量分布（EBT3薄膜与MBO箔片的比较）在5%以内相符。所得图像分辨率（MBO箔片为0.074毫米/像素）与测试的EBT3薄膜（0.085毫米/像素）相当，表明其对于现代放射治疗技术（如质子放射治疗）未来的三维质子剂量验证具有优异性能。
