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含银纳米颗粒的牙科藻酸盐的变形和抗菌性能评估

Evaluation of Deformation and Antibacterial Properties of Dental Alginates Mixed with Silver Nanoparticles.

作者信息

Rivera-Cortés Mario A, Niño-Martínez Nereyda, Ruiz Facundo, Félix-Sicairos Brianda Karina, Martínez-Castañón Gabriel-Alejandro

机构信息

Doctorado Institucional en Ingeniería y Ciencia de los Materiales, Universidad Autónoma de San Luis Potosí, Sierra Leona No. 550, Col. Lomas 2da. Sección, San Luis Potosí C.P. 78210, Mexico.

Facultad de Ciencias, Universidad Autonoma de San Luis Potosí, Av. Parque Chapultepec No. 1570, Privadas del Pedregal, San Luis Potosí C.P. 78295, Mexico.

出版信息

Materials (Basel). 2025 Apr 30;18(9):2069. doi: 10.3390/ma18092069.

Abstract

This study aimed to evaluate the effect of the incorporation of silver nanoparticles (AgNPs) of 5.57 nm size into dental alginates on their deformation and antimicrobial properties. Six experimental groups were prepared: 2 different alginates with 0.25 wt% AgNPs, 2 different alginates with 0.5 wt% AgNPs (5.57 nm), and 2 unmodified control alginate groups. The presence of AgNPs was confirmed using X-ray diffraction analysis with a Bruker D8 Advance diffractometer. Antimicrobial activity was evaluated using the Kirby-Bauer disk diffusion method (direct contact) against and cultures incubated on Mueller-Hinton (M-H) agar at 37 °C for 24 h. The results demonstrated that the addition of 0.25% and 0.5% AgNPs significantly enhanced the antimicrobial properties of alginate ( < 0.05), showing clear inhibition zones against the tested microorganisms. In terms of mechanical properties, AgNPs-modified samples exhibited improved elastic recovery compared to the control group ( > 0.05). These findings suggest that incorporating silver nanoparticles into alginates could enhance their antimicrobial properties without compromising the mechanical integrity required for dental applications.

摘要

本研究旨在评估将尺寸为5.57纳米的银纳米颗粒(AgNPs)掺入牙科藻酸盐中对其变形和抗菌性能的影响。制备了六个实验组:两组不同的藻酸盐分别含有0.25 wt%的AgNPs,两组不同的藻酸盐分别含有0.5 wt%的AgNPs(5.57纳米),以及两组未改性的对照藻酸盐组。使用布鲁克D8 Advance衍射仪通过X射线衍射分析确认了AgNPs的存在。采用 Kirby-Bauer 纸片扩散法(直接接触),针对在穆勒-欣顿(M-H)琼脂上于37°C培养24小时的[具体微生物名称1]和[具体微生物名称2]培养物评估抗菌活性。结果表明,添加0.25%和0.5%的AgNPs显著增强了藻酸盐的抗菌性能(P<0.05),对测试微生物显示出明显的抑菌圈。在机械性能方面,与对照组相比,AgNPs改性的样品表现出更好的弹性恢复(P>0.05)。这些发现表明,将银纳米颗粒掺入藻酸盐中可以增强其抗菌性能,而不会损害牙科应用所需的机械完整性。

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