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添加银纳米粒子的根管生物陶瓷密封剂的推出粘结强度、表面粗糙度和抗菌性能。

The Push-Out Bond Strength, Surface Roughness, and Antimicrobial Properties of Endodontic Bioceramic Sealers Supplemented with Silver Nanoparticles.

机构信息

Doctorado Institucional en Ingeniería y Ciencia de Materiales, Universidad Autónoma de San Luis Potosi, Sierra Leona No. 550 Col. Lomas 2da. Sección, San Luis Potosí 78210, Mexico.

Facultad de Ciencias, Universidad Autónoma de San Luis Potosi, Av. Parque Chapultepec No. 1570, Privadas del Pedregal, San Luis Potosí 78295, Mexico.

出版信息

Molecules. 2024 Sep 18;29(18):4422. doi: 10.3390/molecules29184422.

Abstract

This study evaluated push-out bond test (POBT), surface roughness, and antimicrobial properties against of bioceramic sealers supplemented with silver nanoparticles (AgNPs). The sealers tested were CeraSeal, EndoSequence BC Sealer, and Bio-C Sealer. The POBT was measured with a Universal Testing Machine, and the type of failure was evaluated with a stereomicroscope. The roughness average (Sa) and peak-valley height (Sy) values were evaluated by atomic force microscopy. The bacterial growth inhibition was evaluated using a disk diffusion test, and antimicrobial activity was determined with the plate microdilution method. The POBT showed no significant difference between sealers with and those without NPs in cervical and apical thirds ( > 0.05). In the middle third, the adhesion force was significant for Endosequence BC Sealer ( < 0.05). The results showed that the Sa and Sy parameters, when AgNPs were added, did not show a statistically significant difference compared to the groups without nanoparticles ( > 0.05). All tested sealers showed bacterial growth inhibition, but no significant difference was found. Their efficacy, in descending order of antibacterial activity when AgNPs were added, is as follows: EndoSequence BC Sealer > Bio-C Sealer > CeraSeal. The incorporation of AgNPs into bioceramics improves antimicrobial activity without affecting mechanical properties.

摘要

本研究评估了添加纳米银(AgNPs)的生物陶瓷密封剂的推出力测试(POBT)、表面粗糙度和抗菌性能。测试的密封剂有 CeraSeal、EndoSequence BC 密封剂和 Bio-C 密封剂。POBT 通过万能试验机进行测量,并用体视显微镜评估失效类型。用原子力显微镜评估粗糙度平均值(Sa)和峰谷高度(Sy)值。使用圆盘扩散试验评估细菌生长抑制作用,并用平板微量稀释法测定抗菌活性。POBT 显示在颈部和根尖三分之一处,含 NP 组和不含 NP 组之间没有显著差异( > 0.05)。在中间三分之一处,Endosequence BC 密封剂的粘附力有显著差异( < 0.05)。结果表明,与不含纳米粒子的组相比,添加 AgNPs 后,Sa 和 Sy 参数没有统计学上的显著差异( > 0.05)。所有测试的密封剂都显示出抑制细菌生长的作用,但没有发现显著差异。当添加 AgNPs 时,它们的抗菌活性按降序排列如下:EndoSequence BC 密封剂 > Bio-C 密封剂 > CeraSeal。将 AgNPs 掺入生物陶瓷中可以提高抗菌活性,而不会影响机械性能。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/585e/11434183/dc3eef0714d1/molecules-29-04422-g001.jpg

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