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心脏黏液瘤切除术后的临床特征及手术结果

Clinical characteristics and surgical outcomes following cardiac myxoma resection.

作者信息

Hadiya Nootan, Kumar Madhur, Parshad Rimy, Chandar Poorna, Gupta Anubhav

机构信息

Department of Cardiothoracic & Vascular Surgery Vardhman Mahavir Medical College & Safdarjung Hospital, New Delhi, India.

出版信息

J Cardiovasc Thorac Res. 2025 Mar 18;17(1):35-39. doi: 10.34172/jcvtr.025.33237. eCollection 2025 Mar.

Abstract

INTRODUCTION

Cardiac myxomas are the most common primary cardiac neoplasm (30-50%) with clinical incident of 0.5/ million population. Tranthoracic echocardiography remains the investigation of choice. Surgical excision is curative. The present study aims to analyze demographic and clinical characteristics as well as surgical outcomes in terms of mortality and recurrence of cardiac myxoma.

METHODS

Thirty patients of cardiac myxoma who met the inclusion criteria during study period study period, January-2018 to April-2024 were included. Data was analyzed for demographic characteristics, echocardiographic findings of myxoma and associated valve lesion, associated valve surgery and survival outcome.

RESULTS

Of all subjects, 83.33% presented with dyspnea. Majority of myxoma, 76.67% were attached to interatrial septum. Overall survival at 1- and 3- year was 91.23%. Recurrence free survival at 1-, 3- years and end of this study were 100%, 84.71% and 84.71% respectively. Myxomas with valvular incompetence are rare entity and there is paucity of data and evidences recommending concomitant valve intervention in such cases. There were no immediate peri-operative deaths, however, in contrast to other studies; surgical site infection was the most common post operative complication. Overall survival at 1- and 3- year was 91.23%. Recurrence free survival at 1-, 3- years and end of this study were 100%, 84.71% and 84.71% respectively. Recurrence occurred in first- and third-year following surgery.

CONCLUSION

Study highlights decent outcomes following cardiac myxoma resection. Case specific concomitant valve intervention spiral the success of surgery.

摘要

引言

心脏黏液瘤是最常见的原发性心脏肿瘤(占30 - 50%),临床发病率为每百万人口0.5例。经胸超声心动图仍是首选的检查方法。手术切除可治愈。本研究旨在分析心脏黏液瘤的人口统计学和临床特征以及手术死亡率和复发率等手术结果。

方法

纳入2018年1月至2024年4月研究期间符合纳入标准的30例心脏黏液瘤患者。分析患者的人口统计学特征、黏液瘤的超声心动图表现及相关瓣膜病变、相关瓣膜手术及生存结果。

结果

所有受试者中,83.33%出现呼吸困难。大多数黏液瘤(76.67%)附着于房间隔。1年和3年的总生存率为91.23%。1年、3年及本研究结束时的无复发生存率分别为100%、84.71%和84.71%。伴有瓣膜功能不全的黏液瘤是罕见情况,且缺乏推荐在此类病例中同时进行瓣膜干预的数据和证据。术中无即刻死亡病例,然而,与其他研究不同的是,手术部位感染是最常见的术后并发症。1年和3年的总生存率为91.23%。1年、3年及本研究结束时的无复发生存率分别为100%、84.71%和84.71%。复发发生在术后第一年和第三年。

结论

研究强调心脏黏液瘤切除术后有良好的结果。针对具体病例同时进行瓣膜干预可提高手术成功率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2650/12068802/d28c568eec21/jcvtr-17-35-g001.jpg

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