Holt Anders, Lamberts Morten, Elberling Hanne, Hansen Helene Gjervig
Hjertemedicinsk Afdeling, Københavns Universitetshospital - Herlev og Gentofte Hospital.
Institut for Klinisk Medicin, Københavns Universitet.
Ugeskr Laeger. 2025 May 12;187(20):V11240840. doi: 10.61409/V11240840.
Risk of cardiovascular side effects associated with the agonistic effect on the sympathetic nervous system provided by the medical treatment of ADHD is continuously debated. Any causal relationship has yet to be proven but observational findings suggest an increased risk of cardiovascular disease associated with treatment - especially higher doses over longer periods. Follow-up with clinical assessment, blood pressure, and resting heart rate is advised. Electrocardiograms and measurements of lipid- and HbA1c levels might also often be advisable in adults, as argued in this review.
注意力缺陷多动障碍(ADHD)药物治疗对交感神经系统产生激动作用所带来的心血管副作用风险一直存在争议。任何因果关系尚未得到证实,但观察结果表明,治疗与心血管疾病风险增加有关,尤其是长期使用较高剂量药物时。建议进行临床评估、血压和静息心率随访。正如本综述中所主张的,对于成年人,心电图检查以及血脂和糖化血红蛋白(HbA1c)水平测量通常也可能是可取的。