Sheehan Diana M, Ramírez-Ortiz Daisy, Gwanzura Tendai, Lewis Patrice S, Ertl Melissa M, Duncan Dustin T, Swendeman Dallas, Muñoz-Laboy Miguel, Devieux Jessy G, Trepka Mary Jo
Department of Epidemiology, Robert Stempel College of Public Health and Social Work, Florida International University, 11200 SW 8th St, AHC 5, Room 479, Miami, FL, 33199, USA.
Department of Psychology, University of Minnesota, Minneapolis, MN, USA.
AIDS Behav. 2025 May 15. doi: 10.1007/s10461-025-04756-1.
We assessed the relationship between same-day and next-day antiretroviral therapy (ART) adherence and adherence self-efficacy, daily routine disruptions, mental health, sleep, social support, substance use, and contextual factors in an ecological momentary assessment (EMA) study. Twenty-eight days of data from a convenience sample of 54 18-34-year-old young Latino sexual minority men (YLSMM) was used in generalized mixed models. Participants adhered to ARTs on 96% of 1,306 person-days. Daily motivation to stay healthy, to prevent HIV transmission, and ART self-efficacy were associated with same-day adherence. Routine disruptions, poor sleep, and drug use were associated with same-day non-adherence. Stress was associated with next-day non-adherence, and increased routine disruptions with non-adherence. Findings suggest an opportunity to design and test innovative interventions for YLSMM to improve ART adherence that increase daily adherence motivation and self-efficacy and provide real-time assistance during changes in routine, poor sleep, drug use, and stress.
在一项生态瞬时评估（EMA）研究中，我们评估了当日和次日抗逆转录病毒疗法（ART）依从性与依从性自我效能感、日常活动干扰、心理健康、睡眠、社会支持、物质使用及情境因素之间的关系。我们在广义混合模型中使用了来自54名18至34岁的年轻拉丁裔性少数男性（YLSMM）便利样本的28天数据。在1306人日中，参与者在96%的时间里坚持服用抗逆转录病毒药物。保持健康、预防艾滋病毒传播的日常动力以及抗逆转录病毒疗法自我效能感与当日依从性相关。日常活动干扰、睡眠不佳和药物使用与当日不依从相关。压力与次日不依从相关，日常活动干扰增加与不依从相关。研究结果表明，有机会为年轻拉丁裔性少数男性设计和测试创新干预措施，以提高抗逆转录病毒疗法的依从性，增加每日依从动力和自我效能感，并在日常活动变化、睡眠不佳、药物使用和压力期间提供实时帮助。
JMIR Public Health Surveill. 2023-7-27
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