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从多组学到个性化训练:耐力组学与抗阻组学的兴起

From Multi-omics To Personalized Training: The Rise of Enduromics and Resistomics.

作者信息

Khoramipour Kayvan, Maroto-Izquierdo Sergio, Lista Simone, Santos-Lozano Alejandro, Suzuki Katsuhiko

机构信息

i+HeALTH Strategic Research Group, Department of Health Sciences, Miguel de Cervantes European University (UEMC), Valladolid, 47012, Spain.

Faculty of Sport Sciences, Waseda University, Tokorozawa, Japan.

出版信息

Sports Med Open. 2025 May 14;11(1):52. doi: 10.1186/s40798-025-00855-4.

Abstract

Because of its positive effects on the cardiovascular, metabolic and neurohormonal systems, as well as other aspects of systemic physiology, exercise is crucial to overall health. Traditional exercise physiology techniques that rely on invasive procedures have limited our understanding of the molecular changes induced by exercise. This paper distinguishes the emerging fields of "enduromics" and "resistomics" from sportomics. Enduromics and resistomics concentrate on the molecular responses to endurance and resistance training, respectively, in a variety of populations, whereas sportomics stresses the study of molecular alterations in athletes in competitive or simulated situations. These fields integrate biological systems with omics technology to provide accurate insights into the many physiological responses that occur during aerobic and anaerobic exercise. These methods make it possible to create individualized training plans that maximise health, reduce injury risk and improve adherence by identifying biomarkers and metabolic fingerprints. The revolutionary potential of enduromics and resistomics for athletic performance and public health underscores the need for more research across all demographics and training modalities.

摘要

由于运动对心血管、代谢和神经激素系统以及全身生理学的其他方面具有积极影响,因此运动对整体健康至关重要。传统的运动生理学技术依赖于侵入性程序,限制了我们对运动诱导的分子变化的理解。本文将新兴的“耐力组学”和“抗阻组学”领域与体育组学区分开来。耐力组学和抗阻组学分别专注于各种人群对耐力训练和抗阻训练的分子反应,而体育组学则强调对竞技或模拟情境下运动员分子变化的研究。这些领域将生物系统与组学技术相结合,以准确洞察有氧和无氧运动期间发生的多种生理反应。通过识别生物标志物和代谢指纹,这些方法能够制定个性化训练计划,从而最大限度地提高健康水平、降低受伤风险并提高依从性。耐力组学和抗阻组学对运动表现和公众健康的变革潜力凸显了对所有人口统计学和训练方式进行更多研究的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56ce/12078737/aa5cb49ad346/40798_2025_855_Fig1_HTML.jpg

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