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普通人群中失眠症的患病率:一项荟萃分析。

The Prevalence of Insomnia Disorder in the General Population: A Meta-Analysis.

作者信息

van Straten Annemieke, Weinreich Karl Juri, Fábián Bernát, Reesen Joyce, Grigori Sarah, Luik Annemarie I, Harrer Mathias, Lancee Jaap

机构信息

Department of Clinical, Neuro and Developmental Psychology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.

Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.

出版信息

J Sleep Res. 2025 Oct;34(5):e70089. doi: 10.1111/jsr.70089. Epub 2025 May 14.

Abstract

Insomnia disorder is a significant public health issue, but the prevalence estimates vary widely. We performed a meta-analysis aiming to pool prevalence rates in studies (1) carried out in the general population (2) using a true random sample (3) and using a diagnostic interview, DSM based self-report questions, or a questionnaire with a cut-off established against the DSM criteria. A literature search (in PubMed, Embase, APA PsycInfo) was performed up to April 2024. Two independent reviewers assessed title and abstracts (n = 6732), full-text manuscripts (n = 621) and extracted the data of the 47 included studies. Prevalence rates were pooled using a three-level hierarchical random-effects model, stratified by diagnosis type and adjusted for gender distribution and mean sample age. The pooled prevalence of all studies using an interview to establish the DSM criteria was 12.4% (95% CI: 9.0-16.8%), and of self-report questions assessing the DSM diagnosis 16.3% (95% CI: 11.3%-23.0%). There were 27 studies using different insomnia questionnaires with different cut-offs (prevalence range 7.5%-32.3%). The prevalences differed significantly across regions and high quality studies yielded a lower prevalence rates than lower quality studies. This meta-analysis confirms that insomnia is a common disorder with a prevalence of 12.4 as the most accurate estimate. It also shows the need for standardised ways of assessing insomnia. We think the golden standard is using standardised structured clinical interviews. However, if this is not feasible, we recommend using well validated questionnaires such as the Sleep Condition Indicator or the Insomnia Severity Index. Trial Registration: PROSPERO CRD42023402745.

摘要

失眠症是一个重大的公共卫生问题,但患病率估计差异很大。我们进行了一项荟萃分析,旨在汇总以下研究中的患病率:(1)在普通人群中开展的研究;(2)使用真正随机样本的研究;(3)使用诊断访谈、基于《精神疾病诊断与统计手册》(DSM)的自我报告问题或具有根据DSM标准设定的临界值的问卷的研究。截至2024年4月进行了文献检索(在PubMed、Embase、美国心理学会心理学文摘数据库中)。两名独立评审员评估了标题和摘要(n = 6732)、全文手稿(n = 621),并提取了47项纳入研究的数据。使用三级分层随机效应模型汇总患病率,按诊断类型分层,并针对性别分布和平均样本年龄进行调整。使用访谈来确定DSM标准的所有研究的汇总患病率为12.4%(95%置信区间:9.0%-16.8%),评估DSM诊断的自我报告问题的汇总患病率为16.3%(95%置信区间:11.3%-23.0%)。有27项研究使用了不同的失眠问卷和不同的临界值(患病率范围为7.5%-32.3%)。不同地区的患病率差异显著,高质量研究的患病率低于低质量研究。这项荟萃分析证实失眠是一种常见疾病,最准确的估计患病率为12.4%。它还表明需要标准化的失眠评估方法。我们认为黄金标准是使用标准化的结构化临床访谈。然而,如果这不可行,我们建议使用经过充分验证的问卷,如睡眠状况指标或失眠严重程度指数。试验注册:国际前瞻性系统评价注册库CRD42023402745。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b07/12426706/d8929e2b60eb/JSR-34-e70089-g002.jpg

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