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荷兰精神科门诊患者自然队列中的睡眠障碍:患病率及其与精神病理学症状严重程度和幸福感的关联。

Sleep disorders in a naturalistic cohort of Dutch psychiatric outpatients: prevalence rates and associations with psychopathology symptom severity and well-being.

作者信息

Mijnster Teus, Boersma Gretha J, van Veen Maaike M, Liemburg Edith, Cath Daniëlle, Pijnenborg Gerdina H M, De Jong Peter J, Lancel Marike

机构信息

Centre of Expertise on Sleep and Psychiatry, GGZ Drenthe Mental Health Institute, Assen, The Netherlands.

Department of Clinical Psychology and Experimental Psychopathology, University of Groningen, Groningen, The Netherlands.

出版信息

J Sleep Res. 2024 Apr;33(2):e14009. doi: 10.1111/jsr.14009. Epub 2023 Aug 2.

Abstract

Sleep problems are very common in individuals with a mental disorder. Given the abundant evidence indicating the negative impact of disturbed sleep on mental health outcome, insight into the prevalence of all types of sleep disorders in specific mental disorders and neurodevelopmental conditions is of practical importance. Therefore, we estimated the prevalence of six types of sleep disorders with the Holland Sleep Disorders Questionnaire in an overall mental health sample (n = 1082) and separately for different mental and neurodevelopmental conditions. Furthermore, associations between specific sleep disorders, psychopathology and well-being were studied. The impact of the total number of sleep disorders on these associations was examined. Overall, 46.2% of all participants scored above the cut-off for having a sleep disorder. Specifically, 26.8% scored on insomnia, 12.1% on sleep breathing disorders, 9.7% on hypersomnia, 13.7% on circadian rhythm sleep-wake disorders, 11.2% on parasomnia, and 17.9% on sleep-related movement disorders. Most sleep disorders were associated with greater severity of psychopathology and lower well-being. These associations got stronger with an increasing number of sleep disorders. Our study revealed higher suspected prevalence of most sleep disorders in a mental disorder sample compared to the general population. Moreover, the presence of sleep disorder(s) was strongly associated with symptom severity and reduced well-being. These findings extend the notion that early detection and treatment of sleep disorders in mental health populations is essential for psychiatric outcome.

摘要

睡眠问题在患有精神障碍的个体中非常常见。鉴于大量证据表明睡眠紊乱对心理健康结果有负面影响,了解特定精神障碍和神经发育状况中各类睡眠障碍的患病率具有实际重要意义。因此,我们使用荷兰睡眠障碍问卷在一个整体心理健康样本(n = 1082)中估计了六种睡眠障碍的患病率,并分别针对不同的精神和神经发育状况进行了估计。此外,还研究了特定睡眠障碍、精神病理学和幸福感之间的关联。考察了睡眠障碍总数对这些关联的影响。总体而言,所有参与者中有46.2%的人在睡眠障碍筛查中的得分高于临界值。具体来说,26.8%的人存在失眠问题,12.1%的人存在睡眠呼吸障碍,9.7%的人存在嗜睡症,13.7%的人存在昼夜节律睡眠-觉醒障碍,11.2%的人存在异态睡眠,17.9%的人存在睡眠相关运动障碍。大多数睡眠障碍与更严重的精神病理学症状和更低的幸福感相关。随着睡眠障碍数量的增加,这些关联变得更强。我们的研究表明,与普通人群相比,精神障碍样本中大多数睡眠障碍的疑似患病率更高。此外,睡眠障碍的存在与症状严重程度和幸福感降低密切相关。这些发现进一步证明,在心理健康人群中早期发现和治疗睡眠障碍对精神科治疗结果至关重要。

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