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孤立性动眼神经麻痹作为鞍结节脑膜瘤的首发症状:一例报告

Isolated third cranial nerve palsy as the presenting sign of tuberculum sellae meningioma: a case report.

作者信息

Alotaibi Azizah, Althunayyan Fay, Alshehri Shuroq, Al-Jehani Hosam

机构信息

Department of Neurosurgery, King Fahd University Hospital, Imam Abdulrahman Bin Faisal University, Al Khobar, Saudi Arabia.

College of Medicine, King Fahd University Hospital, Imam Abdulrahman Bin Faisal University, Al Khobar, Saudi Arabia.

出版信息

Front Ophthalmol (Lausanne). 2025 Apr 30;5:1525183. doi: 10.3389/fopht.2025.1525183. eCollection 2025.

Abstract

Tuberculum sellae meningioma (TSM) is an uncommon tumor among all intracranial meningiomas. As these tumors grow, they compress the surrounding structures, including the optic nerves and the pituitary gland. Ocular motor nerve palsy (OMNP) can occur as an isolated mononeuropathy or as part of multiple cranial nerve palsies. The role of corticosteroids in the management of OMNP has not been fully studied in the literature. In this report, we present a case of a previously well middle-aged woman who presented with severe headache and isolated OMNP on examination. MRI of the brain showed a small TSM that extends into the right optic canal. In our case, we noted the expedient and complete recovery of isolated OMNP within a few days following treatment with dexamethasone. This case report is on an isolated OMNP associated with TSM, which has not been previously reported. In addition, it highlights the role of corticosteroids in achieving rapid recovery from OMNP.

摘要

鞍结节脑膜瘤(TSM)在所有颅内脑膜瘤中是一种罕见的肿瘤。随着这些肿瘤的生长,它们会压迫周围结构,包括视神经和垂体。动眼神经麻痹(OMNP)可作为孤立的单神经病出现,或作为多组颅神经麻痹的一部分出现。皮质类固醇在OMNP治疗中的作用在文献中尚未得到充分研究。在本报告中,我们介绍了一例既往健康的中年女性病例,该患者在检查时出现严重头痛和孤立的OMNP。脑部MRI显示一个小的TSM延伸至右侧视神经管。在我们的病例中,我们注意到地塞米松治疗后数天内孤立的OMNP迅速且完全恢复。本病例报告是关于与TSM相关的孤立OMNP,此前尚未有报道。此外,它突出了皮质类固醇在使OMNP快速恢复方面的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3431/12074959/06cde117e909/fopht-05-1525183-g001.jpg

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