Yamamoto Mio, Takahashi Takeshi, Kai Ryota, Hatase Tetsuhisa, Horii Arata
Otolaryngology - Head and Neck Surgery, Niigata University Hospital, Niigata, JPN.
Otolaryngology - Head and Neck Surgery, Niigata University, Niigata, JPN.
Cureus. 2025 Apr 14;17(4):e82226. doi: 10.7759/cureus.82226. eCollection 2025 Apr.
A 67-year-old diabetic man with chronic invasive fungal rhinosinusitis (IFRS) experienced mild, remitting visual symptoms, delaying diagnosis. Despite early MRI evidence of orbital apex inflammation, spontaneous symptom resolution led to discontinuation of hospital visit. Eleven months later, he developed orbital apex syndrome and intracranial complications. Emergency surgery and antifungal therapy were initiated, but vision loss persisted. This case underscores the risk of transient symptom remission masking IFRS progression, emphasizing the importance of early intervention.
一名患有慢性侵袭性真菌性鼻-鼻窦炎（IFRS）的67岁糖尿病男性出现了轻度、间歇性的视觉症状，导致诊断延迟。尽管早期MRI显示眶尖有炎症，但症状的自发缓解导致他中断了就医。11个月后，他发展为眶尖综合征和颅内并发症。随即启动了急诊手术和抗真菌治疗，但视力丧失仍持续存在。该病例强调了短暂症状缓解掩盖IFRS进展的风险，凸显了早期干预的重要性。
