Han Frank
Division of Pediatric Cardiology, Department of Pediatrics, University of Illinois, Chicago, IL, United States.
Division of Pediatric Cardiology, Department of Pediatrics, Connecticut Children's Medical Center, Hartford, CT, United States.
Front Cardiovasc Med. 2025 Apr 30;12:1539958. doi: 10.3389/fcvm.2025.1539958. eCollection 2025.
The spectrum of congenital heart disease is extremely varied, from simple septal defects all the way up to complex heterotaxy with multiple overlapping congenitally malformed regions of the heart. While surgical repair has come a long way since the first congenital cardiac surgery, a B-T-T shunt, an unmet need remains as the population continues to experience sudden cardiac arrest at a greater rate than the general population. Many advances in pacing and cardioversion have occurred to address bradyarrhythmias and tachyarrhythmias, but these carry their own adverse effect profile and limitations. This review aims to survey the field, summarize advances, and provide suggestions for future research directions.
先天性心脏病的范围极为多样,从简单的间隔缺损到复杂的心脏异构,伴有多个重叠的先天性心脏畸形区域。自首次先天性心脏手术(即B-T-T分流术)以来,外科修复技术已经取得了长足的进步,但随着该人群心脏骤停发生率持续高于普通人群,仍存在未满足的需求。在起搏和心脏复律方面已经取得了许多进展,以应对缓慢性心律失常和快速性心律失常,但这些也有其自身的不良反应和局限性。本综述旨在审视该领域,总结进展,并为未来的研究方向提供建议。