Coffman J A, Petty F
Am J Psychiatry. 1985 Oct;142(10):1204-5. doi: 10.1176/ajp.142.10.1204.
Ethanol intoxication has been noted to cause marked changes in brain and CSF levels of gamma-aminobutyric acid (GABA). Using plasma GABA levels to assess brain GABA activity, the authors found that 85 chronic alcoholics had significantly lower levels than control subjects.
乙醇中毒已被证实会导致大脑和脑脊液中γ-氨基丁酸(GABA)水平发生显著变化。作者通过测量血浆GABA水平来评估大脑GABA活性,发现85名慢性酒精中毒患者的血浆GABA水平显著低于对照组。