Rothe K F, Schorer R
Anasth Intensivther Notfallmed. 1985 Jun;20(3):111-8.
This review details basic and clinical aspects of metabolic and respiratory alkalosis and mixed acid-base disturbances. New experimental results show that NH4Cl and arginine-HCl should no longer be used in antialkalotic therapy because they increase intracellular pH and have no effect on intracellular bicarbonate concentration. Appropriate HCl solutions should be employed in severe metabolic alkalosis because they reduce pH and the bicarbonate concentrations in both body compartments.
本综述详细阐述了代谢性碱中毒、呼吸性碱中毒及混合性酸碱紊乱的基础和临床方面。新的实验结果表明,氯化铵和盐酸精氨酸不应再用于抗碱治疗,因为它们会提高细胞内pH值,而对细胞内碳酸氢盐浓度没有影响。对于严重的代谢性碱中毒,应使用合适的盐酸溶液,因为它们可降低身体两个腔室的pH值和碳酸氢盐浓度。