[麻醉学与手术重症监护医学中的酸碱平衡。酸中毒的生理学、病理生理学及临床方面]
[Acid-base homeostasis in anesthesiology and operative intensive care medicine. Physiology, pathophysiology and clinical aspects of acidoses].
作者信息
Rothe K F, Schorer R
出版信息
Anasth Intensivther Notfallmed. 1985 Apr;20(2):69-75.
PMID:2990250
Abstract
Basic and clinical aspects of acid-base physiology and acidoses are reviewed in this paper. Therapeutic principles on the treatment of metabolic and respiratory acidosis are discussed in detail. As far as buffer substances are necessary for antiacidotic therapy, sodium bicarbonate seems to be the agent of choice today. Sodium bicarbonate has a better extra- and intracellular effect than THAM, and should therefore be preferred in every day practice.
摘要
本文综述了酸碱生理学和酸中毒的基础与临床方面。详细讨论了代谢性和呼吸性酸中毒的治疗原则。就抗酸中毒治疗所需的缓冲物质而言，碳酸氢钠似乎是当今的首选药物。碳酸氢钠在细胞外和细胞内的效果均优于三羟甲基氨基甲烷（THAM），因此在日常实践中应优先选用。
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