实验性酸中毒和碱中毒时的胰腺组织pH值
Pancreatic tissue pH in experimental acidosis and alkalosis.
作者信息
Farkas S, Lantos J, Halmágyi G, Molnár Z
出版信息
Acta Med Acad Sci Hung. 1980;37(1):109-14.
The pH was studied in pancreatic tissue and arterial blood in 22 dogs. Respiratory acidosis was induced by CO2 inhalations in 5 dogs, respiratory alkalosis by hyperventilation in 5 dogs, metabolic acidosis by intravenous(i.v.) infusion of 0.1 N HCl in 5 dogs, metabolic alkalosis by i.v. infusion of 4.2% Na bicarbonate in 5 dogs. The differences between the shifts of blood pH and tissue pH were not significant statistically. Infusion of Ringer's solution failed to affect the pH in blood and pancreatic tissue in two control animals. It is concluded, that with an adequate tissue blood flow the pancreatic tissue pH is uninformative unless the blood pH is known.
对22只狗的胰腺组织和动脉血的pH值进行了研究。通过让5只狗吸入二氧化碳诱导呼吸性酸中毒，通过让5只狗过度通气诱导呼吸性碱中毒，通过给5只狗静脉注射0.1N盐酸诱导代谢性酸中毒，通过给5只狗静脉注射4.2%碳酸氢钠诱导代谢性碱中毒。血液pH值变化和组织pH值变化之间的差异无统计学意义。给两只对照动物输注林格氏液未能影响血液和胰腺组织的pH值。得出的结论是，在组织血流充足的情况下，除非知道血液pH值，否则胰腺组织pH值并无参考价值。
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