Hadi Hasan Mahmud, Shimul Md Monir Hossain, Hossain Md Sakhawath, Sultana Afroza, Hossain Md Kamrul, Khandker Salamat, Khan Salim
Department of Public Health, Daffodil International University, Dhaka, Bangladesh.
Healthcare Pharmaceuticals Ltd., Dhaka, Bangladesh.
Endocrinol Diabetes Metab. 2025 May;8(3):e70051. doi: 10.1002/edm2.70051.
Type 2 diabetes mellitus (T2DM) is a growing public health issue in Bangladesh, projected to affect 13.7 million individuals by 2045. Physical inactivity and poor dietary habits increase the risk of complications. This study examined the effects of physical activity and lifestyle modifications on T2DM management.
A case-control study was conducted at Manikganj District Diabetic Hospital with 334 T2DM patients (aged 45-60 years). The case group (n = 167) followed structured physical activity and dietary modifications, while the control group (n = 167) did not. Data on socio-demographics, lifestyle and glycaemic markers-fasting plasma glucose (FPG), postprandial plasma glucose (PPG) and HbA1c-were collected at baseline, 3 months and 6 months. Chi-square tests and ordinal logistic regression models assessed associations between lifestyle factors and glycaemic outcomes.
The control group had significantly higher plasma glucose levels, associated with gender (p < 0.001), treatment type (p = 0.004), medical adherence (p = 0.009), food habits (p = 0.007) and BMI (p = 0.005). The case group showed a significant FPG reduction from 10.035 mmol/L to 6.261 mmol/L (p < 0.001), with similar trends for PPG and HbA1c. Males had 1.8 times higher odds of elevated FPG, while poor adherence increased this risk 2.5-fold.
Lifestyle modifications significantly improve glycaemic control in T2DM patients. Strengthening adherence to medical advice and integrating structured interventions into routine care could enhance diabetes management in Bangladesh.
2型糖尿病（T2DM）在孟加拉国正成为一个日益严重的公共卫生问题，预计到2045年将影响1370万人。缺乏体育活动和不良饮食习惯会增加并发症的风险。本研究探讨了体育活动和生活方式改变对T2DM管理的影响。
在马尼干杰区糖尿病医院对334例T2DM患者（年龄45 - 60岁）进行了病例对照研究。病例组（n = 167）遵循结构化体育活动和饮食调整方案，而对照组（n = 167）未遵循。在基线、3个月和6个月时收集社会人口统计学、生活方式和血糖指标——空腹血糖（FPG）、餐后血糖（PPG）和糖化血红蛋白（HbA1c）的数据。采用卡方检验和有序逻辑回归模型评估生活方式因素与血糖结果之间的关联。
对照组的血糖水平显著更高，这与性别（p < 0.001）、治疗类型（p = 0.004）、药物依从性（p = 0.009）、饮食习惯（p = 0.007）和体重指数（p = 0.005）有关。病例组的FPG从10.035 mmol/L显著降至6.261 mmol/L（p < 0.001），PPG和HbA1c也有类似趋势。男性FPG升高的几率高1.8倍，而依从性差会使这种风险增加2.5倍。
生活方式改变可显著改善T2DM患者的血糖控制。加强对医疗建议的依从性并将结构化干预措施纳入常规护理，可改善孟加拉国的糖尿病管理。
