老年患者使用C-root SP联合不同充填技术进行非手术根管治疗的临床疗效：一项随机对照临床试验

Clinical outcomes of nonsurgical root canal treatment using C-root SP combined with different obturation techniques in older patients: a randomized controlled clinical trial.

作者信息

Dong Liping, Li Jianshe, Xue Peng, Hu Suixin, Xu Chen, Wang Lin, Liu Liu, Luo Qiang, He Huixia, Chen Fei

机构信息

Department of Stomatology, The First Medical Center, Chinese PLA General Hospital, No.28 Fuxing Road, Haidian District, Beijing, 100853, China.

Outpatient Department of TPL, Southern Medical Branch of PLA General Hospital, No.28 Wanshou Road, Haidian District, Beijing, 100858, China.

出版信息

BMC Oral Health. 2025 May 15;25(1):728. doi: 10.1186/s12903-025-06117-9.

DOI:10.1186/s12903-025-06117-9

PMID:40375218

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12082915/

Abstract

BACKGROUND

To evaluate the clinical efficacy and outcomes of C-Root SP bioceramic-based sealers combined with different obturation techniques in nonsurgical root canal treatment for older patients.

METHODS

This prospective, single-center, single-blind, parallel, randomized clinical trial included 240 patients aged ≥ 60 years. Patients were randomly divided into four treatment groups. Group A: C-Root SP combined with single-cone (SC); Group B: C-Root SP combined with warm vertical compaction (WVC); Group C: C-Root SP combined with cold lateral condensation (CLC); Group D: iRoot SP combined with SC (Control). All teeth were subjected to root canal filling using the corresponding methods 7-10 days after root canal preparation and medication. The duration of obturation was recorded. Periapical radiographs were obtained immediately after obturation to determine the length of root canal filling, and postoperative pain on days 1, 2, and 7 was documented. The treatment outcomes based on clinical signs and symptoms as well as periapical index (PAI) were analyzed at 1 year postoperatively.

RESULTS

Groups A and D exhibited significantly higher filling efficiency than groups B and C (P < 0.001). No significant differences were observed in the length of obturation between the groups (P > 0.05). Postoperative pain decreased over time in all groups, with group A showing significantly lower pain rates on day 1 than the other groups (P < 0.05). After 1 year, all groups exhibited considerable reductions in the PAI scores, with success rates ranging from 91.23 to 94.83%; however, no significant differences were observed between them (P > 0.05).

CONCLUSIONS

C-Root SP combined with different obturation techniques yielded similar outcomes to iRoot SP combined with the SC technique in terms of filling length, success rate, and changes in PAI scores. The SC technique demonstrated significant advantages in terms of clinical efficiency and may reduce early postoperative pain when combined with C-Root SP.

TRIAL REGISTRATION

The study was retrospectively registered in chictr.org.cn with the identifier: ChiCTR2400092580 on 11/19/2024.

摘要

背景

评估基于C-Root SP生物陶瓷的封闭剂联合不同充填技术在老年患者非手术根管治疗中的临床疗效及结果。

方法

这项前瞻性、单中心、单盲、平行、随机临床试验纳入了240例年龄≥60岁的患者。患者被随机分为四个治疗组。A组：C-Root SP联合单锥法（SC）；B组：C-Root SP联合热垂直加压法（WVC）；C组：C-Root SP联合冷侧向加压法（CLC）；D组：iRoot SP联合SC法（对照组）。所有牙齿在根管预备和用药7 - 10天后采用相应方法进行根管充填。记录充填时间。充填后立即拍摄根尖片以确定根管充填长度，并记录术后第1、2和7天的疼痛情况。术后1年分析基于临床症状体征以及根尖指数（PAI）的治疗结果。

结果

A组和D组的充填效率显著高于B组和C组（P < 0.001）。各组之间在充填长度上未观察到显著差异（P > 0.05）。所有组的术后疼痛随时间均有减轻，A组在术后第1天的疼痛发生率显著低于其他组（P < 0.05）。1年后，所有组的PAI评分均有显著降低，成功率在91.23%至94.83%之间；然而，各组之间未观察到显著差异（P > 0.