用于银屑病治疗中调节致病性自身抗原和氧化应激的氢键有机框架。
Hydrogen-bonded organic framework for regulating pathogenic autoantigen and oxidative stress in psoriasis treatment.
作者信息
Li Yuhang, Yuan Hui, Cheng Yi-Lun, Li Qiu-Xia, Cao Rong, Li Jin-Lin, Yin Qi, Lu Can-Zhong, Liu Tian-Fu
机构信息
State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, China.
Xiamen Key Laboratory of Rare Earth Photoelectric Functional Materials, Xiamen Institute of Rare Earth Materials, Chinese Academy of Sciences, China.
出版信息
Natl Sci Rev. 2025 Apr 3;12(6):nwaf132. doi: 10.1093/nsr/nwaf132. eCollection 2025 Jun.
This study develops a cobalt porphyrin-based hydrogen-bonded organic framework (Co-HOF) to scavenge reactive oxygen species (ROS) and target the pathogenic peptide LL-37, thereby disrupting psoriasis progression.
本研究开发了一种基于钴卟啉的氢键有机框架（Co-HOF），以清除活性氧（ROS）并靶向致病肽LL-37，从而破坏银屑病的进展。
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