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糖尿病儿童的膳食抗氧化矿物质(铬、镁、铜、硒、锌)及其与空腹和餐后血糖的关系

Dietary Antioxidant Minerals (Cr, Mg, Cu, Se, Zn) in Diabetic Children and their Relationship with Fasting and Postprandial Blood Glucose.

作者信息

Mostafaei Zahra, Paknahad Zamzam, Majdizadeh Golnaz, Djazayery Abolghasem, Movahedi Ariyo

机构信息

Department of Nutrition, Science and Research Branch Islamic Azad University, Tehran, Iran.

Department of Clinical Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran.

出版信息

Int J Prev Med. 2025 Apr 24;16:24. doi: 10.4103/ijpvm.ijpvm_119_24. eCollection 2025.

Abstract

BACKGROUND

Dietary micronutrient levels can influence glucose and insulin regulation. Studies show micronutrients can have a positive effect on blood sugar control. This study aimed to investigate the relationship between blood sugar levels and dietary antioxidant minerals (Cr, Mg, Cu, Se, Zn) in children with type 1 diabetes.

METHODS

This cross-sectional study was conducted on 82 children aged 3-18 with type 1 diabetes. A three-day food record was used to collect dietary information. Fasting blood sugar and 2-hour postprandial glucose were recorded by parents. Dietary data were extracted by N4. SPSS Version 27 was used for all statistical analyses.

RESULTS

The average age of subjects was 10/3 ± 3/3 years. According to the comparison of intake amounts of antioxidant minerals based on age and sex with Recommended Dietary Allowance (RDA), most children reported enough intake. A significant positive relationship was observed between the intake of copper and 2 hours of blood sugar after breakfast ( values < 0.05). We found a significant relationship between intake of chromium, magnesium, selenium, and zinc with blood sugar levels, after adjusting for confounding variables ( values < 0.05).

CONCLUSIONS

The amount of dietary antioxidant minerals in most children was within the appropriate range compared with the RDA. There is a significant relationship between dietary antioxidant minerals (chromium, magnesium, selenium, and zinc) and fasting and postprandial blood glucose after adjusting for confounding variables.

摘要

背景

膳食中的微量营养素水平会影响血糖和胰岛素调节。研究表明,微量营养素对血糖控制有积极作用。本研究旨在探讨1型糖尿病患儿血糖水平与膳食抗氧化矿物质(铬、镁、铜、硒、锌)之间的关系。

方法

本横断面研究对82名3 - 18岁的1型糖尿病患儿进行。采用为期三天的食物记录来收集膳食信息。空腹血糖和餐后2小时血糖由家长记录。膳食数据由N4提取。所有统计分析均使用SPSS 27版。

结果

受试者的平均年龄为10.3±3.3岁。根据基于年龄和性别的抗氧化矿物质摄入量与推荐膳食摄入量(RDA)的比较,大多数儿童报告摄入量充足。早餐后铜的摄入量与2小时血糖之间观察到显著的正相关关系(P值<0.05)。在调整混杂变量后,我们发现铬、镁、硒和锌的摄入量与血糖水平之间存在显著关系(P值<0.05)。

结论

与RDA相比,大多数儿童膳食抗氧化矿物质的量在适当范围内。在调整混杂变量后,膳食抗氧化矿物质(铬、镁、硒和锌)与空腹及餐后血糖之间存在显著关系。

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