Cumpanas Andrei D, Vu Thao N, Tran Candices M, Patel Roshan M
Department of Urology, University of California Irvine, Orange, CA, USA.
Education and Research, Department of Urology, Kidney Stone Center, Division of Endourology, University of California Irvine, 3800 West Chapman Avenue, Suite 7200, Orange, CA, 92868, USA.
Curr Urol Rep. 2025 May 16;26(1):41. doi: 10.1007/s11934-025-01270-8.
There is a high number of acute renal colic cases that present to the emergency department, and it is crucial to have reliable parameters that can accurately predict the likelihood of spontaneous stone passage. In this narrative review, we examined the latest data from the literature regarding the relationship between ureteral wall thickness and the probability of spontaneous stone passage.
The thickness of a normal ureteral wall ranges between 0.95 and 2 mm, with an increase in thickness observed with advancing age. Current data suggests that thinner ureteral wall thickness may favor the spontaneous stone passage. However, the discrepancy between data from the literature is mainly caused by the small study cohorts, heterogeneous protocols, and the intra- and interobserver variability in evaluating non-contrast computed tomography results. There remains a need to better understand the mechanisms behind stone expulsion, as current models rely on oversimplified assumptions about the ureter's biomechanical properties.
急诊科接诊的急性肾绞痛病例数量众多,拥有能够准确预测结石自然排出可能性的可靠参数至关重要。在这篇叙述性综述中,我们研究了文献中关于输尿管壁厚度与结石自然排出概率之间关系的最新数据。
正常输尿管壁厚度在0.95至2毫米之间,随着年龄增长厚度会增加。目前的数据表明,较薄的输尿管壁厚度可能有利于结石自然排出。然而,文献数据之间的差异主要是由研究队列规模小、方案异质性以及评估非增强计算机断层扫描结果时观察者内部和观察者之间的变异性造成的。由于目前的模型对输尿管生物力学特性的假设过于简单,仍有必要更好地了解结石排出背后的机制。