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预测因输尿管结石引起肾绞痛患者结石自行排出的因素。

Predictors for spontaneous stone passage in patients with renal colic secondary to ureteral calculi.

机构信息

Urology Department, University Hospital of Patras, 4th Floor Building A, 26504 Rion-Patra, Greece.

出版信息

Int Urol Nephrol. 2012 Feb;44(1):71-9. doi: 10.1007/s11255-011-9971-4. Epub 2011 May 5.

DOI:10.1007/s11255-011-9971-4
PMID:21544652
Abstract

OBJECTIVES

To determine the clinical, laboratory, and imaging variables that can predict spontaneous stone passage in patients with renal colic secondary to ureteral calculi.

METHODS

We prospectively analyzed the medical records of 114 patients who admitted to the emergency department for renal colic from June until November of 2010. Forty-six of them were excluded. The presence of ureteral calculi was confirmed by either a kidney-ureter-bladder plain film or an ultrasound or a computer tomography. In all patients, a second visit after 1 month was planned and the stone status was checked by the same imaging techniques.

RESULTS

From the 68 patients, 16 had a calculus in the upper ureter, 10 in the mid ureter, and 42 in lower part. Stone size was ranged from 2.3 to 15 mm, 52.9% of them were located in the left ureter and 51.5% were radiopaque. Stones passed spontaneously in 36 patients. In multivariate analysis, serum white blood cell count found to be the most significant predictor (P = 0.028) for spontaneous passage followed by stone size (P = 0.037). In analysis of patients with stone size <10 mm, left side (P = 0.017) and serum white blood cell count (P= 0.032) found to be significant predictors.

CONCLUSIONS

Serum white blood cell count is an easy to assay variable in everyday practice. This study showed that its value, at the acute phase of a renal colic, is a significant predictor for stone spontaneous passage and should be considered. Stone size remains a valuable predictor. Stones <10 mm on the left ureter have a higher likelihood to pass spontaneously.

摘要

目的

确定可以预测继发于输尿管结石的肾绞痛患者自发排石的临床、实验室和影像学变量。

方法

我们前瞻性分析了 2010 年 6 月至 11 月因肾绞痛就诊于急诊的 114 例患者的病历。其中 46 例被排除。通过肾脏-输尿管-膀胱平片或超声或计算机断层扫描确认存在输尿管结石。所有患者均计划在 1 个月后进行第二次就诊,并通过相同的影像学技术检查结石状态。

结果

68 例患者中,16 例结石位于上输尿管,10 例位于中输尿管,42 例位于下输尿管。结石大小为 2.3 至 15 毫米,52.9%位于左侧输尿管,51.5%为不透射线。36 例患者结石自发排出。多变量分析显示,血清白细胞计数是自发排石的最显著预测因子(P = 0.028),其次是结石大小(P = 0.037)。在分析结石大小<10 毫米的患者中,左侧(P = 0.017)和血清白细胞计数(P= 0.032)发现是显著的预测因子。

结论

血清白细胞计数是日常实践中易于检测的变量。本研究表明,其在肾绞痛急性期的值是结石自发排出的重要预测因子,应予以考虑。结石大小仍然是一个有价值的预测因子。左侧<10 毫米的结石更有可能自发排出。

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