Gussen R
Arch Otorhinolaryngol. 1985;242(1):71-6. doi: 10.1007/BF00464410.
The endolymphatic sacs are described in temporal bone specimens from a 31-year-old man with bilateral Mondini disorder. The ducts and sacs are thin-walled, cyst-like structures with complete absence of loose vascular perisac tissue, and are directly apposed to the bone of the vestibular aqueduct. Histological evidence of severe bone erosion is present in these specimens and is most marked in the intermediate and distal portions of the vestibular aqueduct. It is also present in the foveal region of the posterior temporal bone surface underlying the sac. Erosion of the bony wall of the paravestibular canaliculus (PVC) is demonstrable, with incorporation of the vein of the PVC inside the margin of the widened vestibular aqueduct. These findings suggest a causal relationship between pressure within the endolymphatic duct and sac and erosion of the surrounding bone. The absence of endolymphatic hydrops of the cochlea and vestibular organs in the Mondini disorder contrast significantly with the endolymphatic hydrops seen in Meniere's disease.
在内耳颞骨标本中描述了一位患有双侧Mondini畸形的31岁男性的内淋巴囊。内淋巴管和内淋巴囊是薄壁的、囊肿样结构，完全没有疏松的血管周囊组织，并且直接附着于前庭导水管的骨壁。这些标本中存在严重骨侵蚀的组织学证据，在前庭导水管的中部和远端最为明显。在囊下方颞骨后表面的中央凹区域也存在。前庭旁小管（PVC）骨壁的侵蚀是可证实的，PVC的静脉被纳入扩大的前庭导水管边缘内。这些发现提示内淋巴管和内淋巴囊内的压力与周围骨侵蚀之间存在因果关系。Mondini畸形中耳蜗和前庭器官不存在内淋巴积水，这与梅尼埃病中所见的内淋巴积水形成显著对比。
