Gussen R
Arch Otolaryngol. 1982 Sep;108(9):544-9. doi: 10.1001/archotol.1982.00790570010003.
Unimpeded venous drainage of the vestibular organs via the paravestibular canaliculus (PVC) vein is crucial to inner ear fluid mechanisms. With increased venous pressure, insufficient drainage may result in endolymphatic hydrops, unless collateral veins develop. Different mechanisms cause venous insufficiency in different cases of Meniere's. One suggested mechanism is alteration of the intermediate endolymphatic sac (IES) microcirculation with decreased regulation of blood held within subepithelial capillaries of the sac. Increased blood may thus drain into the veins, with increased venous pressure and inadequate vestibular drainage. Altered microcirculation may be morphological as in fibrosis or shortening of the IES, or physiological where the microcirculation receives abnormal stimuli or reacts abnormally to normal stimuli. Venous insufficiency may result from PVC vein anomalies. Variations in venous pattern whereby vestibular organs preponderantly drain through the PVC vein may predispose to Meniere's disease.
前庭器官通过前庭旁小管（PVC）静脉实现不受阻碍的静脉引流，这对内耳液体机制至关重要。随着静脉压力升高，除非侧支静脉形成，引流不足可能导致内淋巴积水。在不同的梅尼埃病病例中，不同机制会导致静脉功能不全。一种提出的机制是中间内淋巴囊（IES）微循环改变，囊上皮下毛细血管内血液的调节减少。因此，更多血液可能流入静脉，导致静脉压力升高和前庭引流不足。微循环改变可能是形态学上的，如IES纤维化或缩短，也可能是生理学上的，即微循环受到异常刺激或对正常刺激反应异常。静脉功能不全可能由PVC静脉异常引起。前庭器官主要通过PVC静脉引流的静脉模式变化可能易患梅尼埃病。
