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Kinetics of enzymes requiring long-chain acyl-CoA esters as substrates: effects of substrate binding to albumin.

作者信息

Bartlett K, Bartlett P, Bartlett N, Sherratt H S

出版信息

Biochem J. 1985 Jul 15;229(2):559-60. doi: 10.1042/bj2290559.

DOI:10.1042/bj2290559
PMID:4038281
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1145092/
Abstract
摘要

相似文献

1
Kinetics of enzymes requiring long-chain acyl-CoA esters as substrates: effects of substrate binding to albumin.以长链酰基辅酶A酯为底物的酶的动力学：底物与白蛋白结合的影响。
Biochem J. 1985 Jul 15;229(2):559-60. doi: 10.1042/bj2290559.
2
Importance of acyl-CoA availability in interpretation of carnitine palmitoyltransferase I kinetics.
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3
Acyl-CoA chain length affects the specificity of various carnitine palmitoyltransferases with respect to carnitine analogues. Possible application in the discrimination of different carnitine palmitoyltransferase activities.酰基辅酶A链长度影响各种肉碱棕榈酰转移酶对肉碱类似物的特异性。可能应用于区分不同的肉碱棕榈酰转移酶活性。
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4
Interacting effects of L-carnitine and malonyl-CoA on rat liver carnitine palmitoyltransferase.左旋肉碱与丙二酰辅酶A对大鼠肝脏肉碱棕榈酰转移酶的相互作用
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Malonyl-CoA binding site and the overt carnitine palmitoyltransferase activity reside on the opposite sides of the outer mitochondrial membrane.丙二酰辅酶A结合位点和明显的肉碱棕榈酰转移酶活性位于线粒体外膜的两侧。
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Hysteretic behaviour of carnitine palmitoyltransferase. The effect of preincubation with malonyl-CoA.肉碱棕榈酰转移酶的滞后行为。丙二酰辅酶A预温育的影响。
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7
Purification and properties of the soluble carnitine palmitoyltransferase from bovine liver mitochondria.牛肝线粒体可溶性肉碱棕榈酰转移酶的纯化及性质
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Observations on the affinity for carnitine, and malonyl-CoA sensitivity, of carnitine palmitoyltransferase I in animal and human tissues. Demonstration of the presence of malonyl-CoA in non-hepatic tissues of the rat.关于动物和人体组织中肉碱棕榈酰转移酶I对肉碱的亲和力及丙二酰辅酶A敏感性的观察。大鼠非肝脏组织中丙二酰辅酶A存在的证明。
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10
Effect of a biguanide (buformin) on carnitine palmitoyltransferase activity.
Acta Biochim Biophys Acad Sci Hung. 1977;12(3):217-21.

引用本文的文献

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The malonyl-CoA-long-chain acyl-CoA axis in the maintenance of mammalian cell function.丙二酰辅酶A-长链酰基辅酶A轴在维持哺乳动物细胞功能中的作用
Biochem J. 1999 Nov 1;343 Pt 3(Pt 3):505-15.
2
Influence of diet on the kinetic behavior of hepatic carnitine palmitoyltransferase I toward different acyl CoA esters.饮食对肝脏肉碱棕榈酰转移酶I针对不同酰基辅酶A酯的动力学行为的影响。
Lipids. 1997 Jan;32(1):31-7. doi: 10.1007/s11745-997-0005-4.
3
Restoration of the properties of carnitine palmitoyltransferase I in liver mitochondria during re-feeding of starved rats.饥饿大鼠重新进食期间肝脏线粒体中肉碱棕榈酰转移酶I活性的恢复
Biochem J. 1986 Oct 15;239(2):485-8. doi: 10.1042/bj2390485.
4
Enzymes of carnitine acylation. Is overt carnitine palmitoyltransferase of liver peroxisomal carnitine octanoyltransferase?肉碱酰化酶。肝脏过氧化物酶体肉碱辛酰转移酶的明显肉碱棕榈酰转移酶是吗？
Biochem J. 1988 Jan 1;249(1):231-7. doi: 10.1042/bj2490231.
5
Liposomes as carriers of poorly water-soluble substrates: linear modelling of membrane systems with catalytic or binding sites of different facedness. Significance of experimental membrane partition coefficients and of kinetic and equilibrium parameters.脂质体作为难溶性底物的载体：具有不同朝向催化或结合位点的膜系统的线性建模。实验性膜分配系数以及动力学和平衡参数的意义。
Biochem J. 1988 Aug 15;254(1):101-8. doi: 10.1042/bj2540101.
6
Testing and characterizing enzymes and membrane-bound carrier proteins acting on amphipathic ligands in the presence of bilayer membrane material and soluble binding protein. Application to the uptake of oleate into isolated cells.在存在双层膜材料和可溶性结合蛋白的情况下，对作用于两亲性配体的酶和膜结合载体蛋白进行检测和表征。应用于油酸进入分离细胞的摄取过程。
Biochem J. 1992 Jun 1;284 ( Pt 2)(Pt 2):353-61. doi: 10.1042/bj2840353.

本文引用的文献

1
A re-examination of some properties of fatty acyl-CoA micelles.对脂肪酰辅酶A胶束某些性质的重新审视。
J Biol Chem. 1981 Dec 25;256(24):12740-7.
2
Response to starvation of hepatic carnitine palmitoyltransferase activity and its regulation by malonyl-CoA. Sex differences and effects of pregnancy.肝脏肉碱棕榈酰转移酶活性对饥饿的反应及其受丙二酰辅酶A的调节。性别差异及妊娠的影响。
Biochem J. 1982 Dec 15;208(3):673-8. doi: 10.1042/bj2080673.
3
Importance of albumin binding in the assay for carnitine palmitoyltransferase.白蛋白结合在肉碱棕榈酰转移酶测定中的重要性。
Biochem J. 1983 Nov 15;216(2):495-8. doi: 10.1042/bj2160495.
4
Differences in the sensitivity of carnitine palmitoyltransferase to inhibition by malonyl-CoA are due to differences in Ki values.肉碱棕榈酰转移酶对丙二酸单酰辅酶A抑制的敏感性差异是由于Ki值的不同。
J Biol Chem. 1984 Oct 10;259(19):12030-3.
5
Some physical properties of palmityl-coenzyme A micelles.棕榈酰辅酶A胶束的一些物理性质。
Biochim Biophys Acta. 1968 Sep 2;164(1):1-11. doi: 10.1016/0005-2760(68)90065-9.
6
Carnitine palmitoyltransferase I. The site of inhibition of hepatic fatty acid oxidation by malonyl-CoA.肉碱棕榈酰转移酶I。丙二酰辅酶A对肝脏脂肪酸氧化的抑制位点。
J Biol Chem. 1978 Jun 25;253(12):4128-36.
7
Purification and characterization of a long-chain acyl-CoA hydrolase from rat liver microsomes.大鼠肝脏微粒体长链酰基辅酶A水解酶的纯化与特性分析
Biochim Biophys Acta. 1979 Aug 30;574(2):321-33. doi: 10.1016/0005-2760(79)90013-4.