肉碱棕榈酰转移酶I。丙二酰辅酶A对肝脏脂肪酸氧化的抑制位点。 - Suppr

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超能文献

Carnitine palmitoyltransferase I. The site of inhibition of hepatic fatty acid oxidation by malonyl-CoA.

作者信息

McGarry J D, Leatherman G F, Foster D W

出版信息

J Biol Chem. 1978 Jun 25;253(12):4128-36.

PMID:659409

Abstract

摘要

相似文献

Carnitine palmitoyltransferase I. The site of inhibition of hepatic fatty acid oxidation by malonyl-CoA.肉碱棕榈酰转移酶I。丙二酰辅酶A对肝脏脂肪酸氧化的抑制位点。

J Biol Chem. 1978 Jun 25;253(12):4128-36.

Effect of pH on malonyl-CoA inhibition of carnitine palmitoyltransferase I.pH对丙二酰辅酶A抑制肉碱棕榈酰转移酶I的影响。

Biochem J. 1983 May 15;212(2):521-4. doi: 10.1042/bj2120521.

Effects of fasting and malonyl CoA on the kinetics of carnitine palmitoyltransferase and carnitine octanoyltransferase in intact rat liver mitochondria.禁食和丙二酰辅酶A对完整大鼠肝脏线粒体中肉碱棕榈酰转移酶和肉碱辛酰转移酶动力学的影响。

FEBS Lett. 1981 Sep 28;132(2):166-8. doi: 10.1016/0014-5793(81)81152-0.

Involvement of hysteretic effects in the inhibition of carnitine palmitoyltransferase by malonyl-CoA.丙二酰辅酶A对肉碱棕榈酰转移酶抑制作用中的滞后效应参与情况。

Biochem J. 1984 Dec 15;224(3):1015-8. doi: 10.1042/bj2241015.

Altered sensitivity of carnitine palmitoyltransferase to inhibition by malonyl-CoA in ketotic diabetic rats.酮症糖尿病大鼠中肉碱棕榈酰转移酶对丙二酰辅酶A抑制作用的敏感性改变。

Biochem J. 1984 Apr 1;219(1):337-9. doi: 10.1042/bj2190337.

Ethanol increases the sensitivity of carnitine palmitoyltransferase I to inhibition by malonyl-CoA in short-term hepatocyte incubations.在短期肝细胞培养中，乙醇会增加肉碱棕榈酰转移酶I对丙二酰辅酶A抑制作用的敏感性。

Biochim Biophys Acta. 1989 Apr 26;1002(3):405-8. doi: 10.1016/0005-2760(89)90358-5.

Increased sensitivity of carnitine palmitoyltransferase I activity to malonyl-CoA inhibition after preincubation of intact rat liver mitochondria with micromolar concentrations of malonyl-CoA in vitro.在体外将完整大鼠肝脏线粒体与微摩尔浓度的丙二酰辅酶A预孵育后，肉碱棕榈酰转移酶I活性对丙二酰辅酶A抑制作用的敏感性增加。

Biochem J. 1983 Mar 15;210(3):953-6. doi: 10.1042/bj2100953.

Sensitivity of carnitine acyltransferase I to malonly-CoA inhibition in isolated rat liver mitochondria is quantitatively related to hepatic malonyl-CoA concentration in vivo.在分离的大鼠肝脏线粒体中，肉碱酰基转移酶I对丙二酰辅酶A抑制作用的敏感性与体内肝脏丙二酰辅酶A浓度存在定量关系。

Biochem J. 1982 Jul 15;206(1):177-9. doi: 10.1042/bj2060177.

Carnitine palmitoyltransferase (CPT2) from liver mitochondrial inner membrane becomes inhibitable by malonyl-CoA if reconstituted with outer membrane malonyl-CoA binding protein.如果用外膜丙二酰辅酶A结合蛋白进行重组，来自肝线粒体内膜的肉碱棕榈酰转移酶（CPT2）会被丙二酰辅酶A抑制。

FEBS Lett. 1990 Sep 3;269(2):406-8. doi: 10.1016/0014-5793(90)81204-2.

Differences in the sensitivity of carnitine palmitoyltransferase to inhibition by malonyl-CoA are due to differences in Ki values.肉碱棕榈酰转移酶对丙二酸单酰辅酶A抑制的敏感性差异是由于Ki值的不同。

J Biol Chem. 1984 Oct 10;259(19):12030-3.

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