Coller Barry S
Rockefeller University, New York, NY, USA.
J Clin Transl Sci. 2025 Feb 25;9(1):e88. doi: 10.1017/cts.2024.691. eCollection 2025.
The COVID-19 pandemic laid bare the inequities in U.S. healthcare in ways that captured public attention and reinforced the need to view all of healthcare through an equity lens. It also exposed global inequities in access to healthcare technologies. At Rockefeller University, we participate in the entire spectrum of translational research, but our focus is in the areas of basic research and new methods to prevent, diagnose, and treat disease, extending to proof of concept preclinical and Phase 1 studies. Since we believe that all phases of translational research should have an equity lens, we have instituted an initiative to encourage thought and planning about global equitable access to discoveries made by our trainee Clinical Scholars and faculty, even at the earliest phases of basic research. Assuring global equitable access to new technologies requires addressing at least 3 different aspects of new technology: 1. Patenting and licensing, 2. Manufacturing, and 3. Dissemination and implementation in low- and middle-income countries. In this review, I focus on patenting and licensing and offer ten questions for inventors to consider in discussing licensing their technologies with technology transfer officers to maximize equitable global access to the technologies they create.
新冠疫情暴露了美国医疗保健领域的不平等现象，这些现象引起了公众关注，并强化了通过公平视角看待整个医疗保健体系的必要性。它还揭示了全球在获取医疗技术方面的不平等。在洛克菲勒大学，我们参与了整个转化研究领域，但我们的重点是基础研究以及预防、诊断和治疗疾病的新方法，范围延伸到概念验证临床前研究和1期研究。由于我们认为转化研究的各个阶段都应具备公平视角，我们发起了一项倡议，鼓励人们思考并规划如何让我们的临床学者学员和教员所取得的研究成果在全球范围内实现公平获取，即使是在基础研究的最早期阶段。确保全球公平获取新技术需要解决新技术至少三个不同方面的问题：1. 专利与许可；2. 制造；3. 在低收入和中等收入国家的推广与应用。在这篇综述中，我将重点关注专利与许可，并提出十个问题供发明人在与技术转让官员讨论技术许可时思考，以便最大程度地实现全球公平获取他们所创造的技术。
