以尿失禁为首发症状的儿童泌尿生殖系统横纹肌肉瘤：一例报告及文献复习

Genitourinary rhabdomyosarcoma in a child with urinary incontinence as the initial symptom: A case report and literature review.

作者信息

Wu Jingde, Ma Rong, Zhang Qingwei, Xie Jianlin, Huang Xiande

机构信息

The First Clinical Medical College of Gansu University of Chinese Medicine (Gansu Provincial Hospital), Lanzhou, China.

Department of Urology, Gansu Provincial Hospital, Lanzhou, China.

出版信息

Urol Case Rep. 2025 Apr 23;61:103051. doi: 10.1016/j.eucr.2025.103051. eCollection 2025 Jul.

DOI:10.1016/j.eucr.2025.103051

PMID:40385459

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12084403/

Abstract

Rhabdomyosarcoma (RMS) is a morphologically heterogeneous high-grade malignancy that occurs uncommonly in the pediatric genitourinary (GU) system, and the most typical clinical symptoms are urinary frequency, urgency, hematuria, and associated with infection. The boys in this case, persistent urinary incontinence was relatively rare, and it was easily misdiagnosed as pediatric urinary incontinence in clinical diagnosis. Incontinence disease and lower urinary tract symptoms were identified by imaging examination, and final pathological biopsy confirmed the diagnosis of pediatric GU embryonal rhabdomyosarcoma (ERMS). Learning through case report and literature can help clinicians to better understand the manifestations and accurate diagnostic treatment of the disease.

摘要

横纹肌肉瘤（RMS）是一种形态学上异质性的高级别恶性肿瘤，在小儿泌尿生殖系统（GU）中罕见发生，最典型的临床症状是尿频、尿急、血尿，并伴有感染。该病例中的男孩持续性尿失禁相对少见，在临床诊断中容易被误诊为小儿尿失禁。通过影像学检查发现失禁疾病和下尿路症状，最终病理活检确诊为小儿GU胚胎性横纹肌肉瘤（ERMS）。通过病例报告和文献学习有助于临床医生更好地了解该疾病的表现及准确的诊断治疗。