Ndukwe Munachiso I, Pohankova Denisa, Halada Petr, Laco Jan, Stepan Martin, Reslova Tatana, Bretova Petra, Karasek Dominik, Habes Domink, Rezac Adam, Sirak Igor
Department of Obstetrics and Gynaecology, University Hospital Hradec Kralove, Charles University, Faculty of Medicine, Hradec Kralove, CZE.
Department of Oncology and Radiotherapy, University Hospital Hradec Kralove, Charles University, Faculty of Medicine, Hradec Králove, CZE.
Cureus. 2025 Apr 18;17(4):e82486. doi: 10.7759/cureus.82486. eCollection 2025 Apr.
The management of cervical cancer during the first trimester of pregnancy requires a multidisciplinary approach that considers medical, psychological, and social factors. This report details the case of a patient diagnosed preoperatively with bulky early-stage cervical cancer at nine weeks of gestation, during an evaluation initially intended for pregnancy termination. While definitive chemoradiotherapy is the standard treatment for early-stage bulky cervical tumors, the treatment strategy, in this case, was influenced by the patient's decision to terminate the pregnancy without delay. A radical hysterectomy with pelvic lymphadenectomy was successfully performed at 10 weeks of gestation. The patient experienced an uneventful postoperative recovery and was subsequently advised to undergo adjuvant chemoradiotherapy. This case underscores the importance of an individualized management plan that prioritizes maternal health while respecting reproductive rights and patient autonomy.
妊娠早期宫颈癌的管理需要采取多学科方法，综合考虑医学、心理和社会因素。本报告详细介绍了一名患者的病例，该患者在妊娠9周时术前被诊断为体积较大的早期宫颈癌，最初评估目的是终止妊娠。虽然根治性放化疗是早期体积较大宫颈癌的标准治疗方法，但在本例中，治疗策略受患者希望立即终止妊娠这一决定的影响。在妊娠10周时成功进行了根治性子宫切除术及盆腔淋巴结清扫术。患者术后恢复顺利，随后被建议接受辅助放化疗。该病例强调了制定个性化管理计划的重要性，即在尊重生殖权利和患者自主权的同时，优先考虑孕产妇健康。
