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可切除非小细胞肺癌的围手术期免疫治疗策略

Perioperative immunotherapy strategies for resectable non-small cell lung cancer.

作者信息

Marchal Corynne, Eberst Guillaume, Calais François, Westeel Virginie, Malouf Reem

机构信息

Marie & Louis Pasteur University, Besançon, France.

Department of Chest Diseases and Thoracic Oncology, University Hospital of Besançon, Besançon, France.

出版信息

Cochrane Database Syst Rev. 2025 May 19;5(5):CD015819. doi: 10.1002/14651858.CD015819.

DOI:10.1002/14651858.CD015819
PMID:40386901
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12086965/
Abstract

This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To compare, via a network meta-analysis, the effectiveness and safety of different immunotherapy agents that are administered in a perioperative setting to people with resectable non small-cell lung cancer To perform indirect comparisons in order to generate a clinically meaningful hierarchy of perioperative strategies of immunotherapy administration for overall survival in operable people with resectable non small-cell lung cancer.

摘要

这是一项Cochrane系统评价(干预措施)的方案。目标如下:通过网络荟萃分析,比较在围手术期给予可切除非小细胞肺癌患者不同免疫治疗药物的有效性和安全性;进行间接比较,以便为可切除非小细胞肺癌的可手术患者生成关于围手术期免疫治疗总体生存策略的具有临床意义的等级排序。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c535/12086965/d758f815ff06/nCD015819-FIG-01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c535/12086965/d758f815ff06/nCD015819-FIG-01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c535/12086965/d758f815ff06/nCD015819-FIG-01.jpg

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本文引用的文献

1
A Review of Immunotherapy in Non-Small-Cell Lung Cancer.免疫疗法在非小细胞肺癌中的研究进展
Curr Oncol. 2024 Jun 17;31(6):3495-3512. doi: 10.3390/curroncol31060258.
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The Proposed Ninth Edition TNM Classification of Lung Cancer.肺癌第九版 TNM 分期系统。
Chest. 2024 Oct;166(4):882-895. doi: 10.1016/j.chest.2024.05.026. Epub 2024 Jun 15.
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Perioperative Nivolumab in Resectable Lung Cancer.可切除肺癌的围手术期纳武利尤单抗。
N Engl J Med. 2024 May 16;390(19):1756-1769. doi: 10.1056/NEJMoa2311926.
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Top advances of the year: Perioperative therapy for lung cancer.年度重大进展:肺癌围手术期治疗。
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Neoadjuvant Chemo-Immunotherapy for Early-Stage Non-Small Cell Lung Cancer: A Systematic Review and Meta-Analysis.新辅助化疗免疫治疗早期非小细胞肺癌:系统评价和荟萃分析。
JAMA Netw Open. 2024 Apr 1;7(4):e246837. doi: 10.1001/jamanetworkopen.2024.6837.
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The Emerging Role of Immunotherapy in Resectable Non-Small Cell Lung Cancer.免疫疗法在可切除非小细胞肺癌中的新作用。
Ann Thorac Surg. 2024 Jul;118(1):119-129. doi: 10.1016/j.athoracsur.2024.01.024. Epub 2024 Feb 3.
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The International Association for the Study of Lung Cancer Staging Project for Lung Cancer: Proposals for the Revision of the N Descriptors in the Forthcoming Ninth Edition of the TNM Classification for Lung Cancer.国际肺癌研究协会肺癌分期项目:即将出版的第九版肺癌 TNM 分类中 N 描述符修订建议。
J Thorac Oncol. 2024 May;19(5):766-785. doi: 10.1016/j.jtho.2023.10.012. Epub 2023 Oct 20.
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The global burden of lung cancer: current status and future trends.全球肺癌负担:现状与未来趋势。
Nat Rev Clin Oncol. 2023 Sep;20(9):624-639. doi: 10.1038/s41571-023-00798-3. Epub 2023 Jul 21.
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Perioperative Pembrolizumab for Early-Stage Non-Small-Cell Lung Cancer.帕博利珠单抗用于早期非小细胞肺癌的围手术期治疗。
N Engl J Med. 2023 Aug 10;389(6):491-503. doi: 10.1056/NEJMoa2302983. Epub 2023 Jun 3.
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CINeMA: Software for semiautomated assessment of the confidence in the results of network meta-analysis.CINeMA:用于半自动评估网络荟萃分析结果可信度的软件。
Campbell Syst Rev. 2020 Mar 11;16(1):e1080. doi: 10.1002/cl2.1080. eCollection 2020 Mar.