Wan Jiachen, Fang Ruojiao, Liu Ping, Bi Yajie, Luo Shu, Cao Chengqi, Wang Li
Laboratory for Traumatic Stress Studies, State Key Laboratory of Cognitive Science and Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, People's Republic of China.
Department of Psychology, University of Chinese Academy of Sciences, Beijing, People's Republic of China.
Eur J Psychotraumatol. 2025 Dec;16(1):2501824. doi: 10.1080/20008066.2025.2501824. Epub 2025 May 19.
Posttraumatic stress disorder (PTSD) is a mental disorder comprised of heterogeneous clinical symptoms. Various studies have demonstrated that anhedonia is a distinct symptom dimension of PTSD. However, the association between anhedonia dimension and different aspects of PTSD symptomatology remains unclear. This study examined the associations between anhedonia symptoms and PTSD diagnosis, overall symptom severity, and both psychosocial and physical functional impairments. A total of 1,063 adult survivors of the 2008 Wenchuan earthquake were assessed nine years after the disaster. PTSD symptoms and functional outcomes were measured using the PTSD Checklist for DSM-5 (PCL-5) and the Short Form Health Survey (SF-36). Multiple regression analyses were conducted to examine the associations between anhedonia and key outcomes, controlling for relevant covariates. Partial correlation analyses were used to provide supplementary effect size estimates. Anhedonia symptoms were significantly associated with both PTSD diagnosis and levels of overall symptoms, and specifically associated with psychosocial function impairments rather than physical function impairments. Relative to the other PTSD symptom dimensions anhedonia showed the second highest correlation with PTSD diagnosis and levels of overall symptoms and medium correlation with psychosocial function impairments. These findings suggest that anhedonia may represent an important symptom dimension within PTSD, particularly in relation to symptom severity and psychosocial functioning. The results highlight the potential value of further investigating anhedonia in both PTSD assessment and cross-diagnostic research.
创伤后应激障碍（PTSD）是一种包含多种临床症状的精神障碍。多项研究表明，快感缺失是PTSD的一个独特症状维度。然而，快感缺失维度与PTSD症状学不同方面之间的关联仍不明确。本研究考察了快感缺失症状与PTSD诊断、总体症状严重程度以及心理社会和身体功能损害之间的关联。对2008年汶川地震的1063名成年幸存者在灾难发生九年后进行了评估。使用《精神疾病诊断与统计手册》第5版创伤后应激障碍检查表（PCL-5）和简短健康调查（SF-36）测量PTSD症状和功能结局。进行多元回归分析以考察快感缺失与关键结局之间的关联，并对相关协变量进行控制。使用偏相关分析来提供补充效应量估计。快感缺失症状与PTSD诊断和总体症状水平均显著相关，并且特别与心理社会功能损害相关，而非与身体功能损害相关。相对于其他PTSD症状维度，快感缺失与PTSD诊断和总体症状水平的相关性第二高，与心理社会功能损害的相关性为中等。这些发现表明，快感缺失可能是PTSD中的一个重要症状维度，特别是在症状严重程度和心理社会功能方面。结果凸显了在PTSD评估和跨诊断研究中进一步研究快感缺失的潜在价值。
