Fedorova N L, Markelov B A, Shafirkin A V, Pliukhina G Ia
Radiobiologiia. 1985 Jan-Feb;25(1):69-73.
A study was made of the descendants of 12 male dogs subjected to gamma-irradiation during six years at dose-rates of 0.0034 Gy/day and 0.0017 Gy/day + additional annual exposures to gamma-radiation three times a year each of 0.42 Gy. The observations were made during 3 years after the end of irradiation. It was shown that the descendants reflected the regularities of the disorders revealed in fathers' spermatogenesis. The radiobiological effects were function of dose--rate and cumulative radiation dose. The changes were mainly noted during embryogenesis and manifested by the sterility, mortinatality and the decreased number of puppies in the postreity.
对12只雄性犬的后代进行了研究,这些雄性犬在6年时间里分别以0.0034 Gy/天和0.0017 Gy/天的剂量率接受γ射线照射,并且每年额外接受3次每次0.42 Gy的γ射线照射。在照射结束后的3年里进行了观察。结果表明,后代反映了父本精子发生中所揭示的紊乱规律。放射生物学效应是剂量率和累积辐射剂量的函数。这些变化主要在胚胎发生期间被观察到,表现为不育、死亡率增加以及后代幼犬数量减少。