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[胚胎发育过程中接受分次电离辐射作用的小鼠遗传性疾病发生率]

[The yield of genetic disorders in mice exposed to the action of fractionated ionizing radiation in embryogenesis].

作者信息

Pomerantseva M D, Ramaĭia L K

出版信息

Radiobiologiia. 1990 May-Jun;30(3):339-43.

PMID:2371392
Abstract

In studying the occurrence of genetic lesions in mice subjected to daily long-term gamma-irradiation at different periods of the antenatal development, increased preimplantation losses were revealed in offspring of females irradiated with a cumulative dose of 1.25-3.5 Gy. In male offspring the death rate did not significantly vary from the control, but the incidence of abnormal spermatozoa heads and reciprocal translocations in spermatocytes was increased.

摘要

在研究孕期不同阶段每天接受长期伽马辐射的小鼠遗传损伤的发生情况时,发现累积剂量为1.25 - 3.5 Gy的辐射雌性小鼠的后代中,植入前损失增加。雄性后代的死亡率与对照组相比无显著差异,但精子头部异常和精母细胞相互易位的发生率增加。

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