Diesch Sophia, Frank Konstantin, Brébant Vanessa, Bohusch Sebastian, Brix Eva, Zeng Rui, Prantl Lukas
Department of Plastic, Hand and Reconstructive Surgery, University Hospital Regensburg, Regensburg, Germany.
Department for Hand, Plastic and Aesthetic Surgery, Ludwig - Maximilian University Munich, Munich, Germany.
Aesthetic Plast Surg. 2025 May 19. doi: 10.1007/s00266-025-04875-z.
Lip augmentation is a highly demanded cosmetic procedure due to the association of full lips with youth, beauty, and sensuality. Among various techniques, autologous fat grafting, particularly with the cell-enriched lipotransfer (CELT) method, has emerged as a natural and long-lasting option. Unlike hyaluronic acid fillers, which require regular touch-ups, CELT offers sustained volume retention and potentially higher patient satisfaction.
This study aimed to assess patient satisfaction following lip augmentation using the CELT technique and compare it with traditional fat preparation methods, such as sedimentation and filtration. The study also sought to evaluate the influence of other variables, including gender, age, and fat injection volume, on satisfaction outcomes.
A retrospective chart review of patients who underwent lip augmentation with autologous fat grafting was conducted. Satisfaction was measured using the FACE-Q questionnaire, focusing on various lip-related aspects such as shape, fullness, and how well the lips suited the face. The study compared satisfaction outcomes between the CELT method and combined sedimentation/filtration techniques. Statistical analysis using the Kruskal-Wallis test and Pearson's correlation was performed to assess the influence of preparation method, injected volume, and patient demographics.
The CELT method consistently produced higher satisfaction compared to sedimentation and filtration (p < 0.001 for all items). Patients treated with CELT reported greater improvements in the shape of the lips, fullness of the lower lip, and Cupid's bow. Gender and age were also significant factors, with males showing greater satisfaction in smile-related aspects, while females were more satisfied with the lip style. Older patients reported greater improvements in how well their lips suited their face, while higher injected volumes positively correlated with lip fullness and appearance.
The CELT fat grafting technique significantly enhances patient satisfaction in lip augmentation compared to traditional fat preparation methods. CELT's higher fat retention and more natural results make it a superior option for lip augmentation. However, further studies incorporating objective volumetric measurements are needed to validate these findings.
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由于丰满的嘴唇与年轻、美丽和性感相关联，唇部填充是一种需求很高的美容手术。在各种技术中，自体脂肪移植，特别是采用富含细胞的脂肪移植（CELT）方法，已成为一种自然且持久的选择。与需要定期补充的透明质酸填充剂不同，CELT能持续保持体积，患者满意度可能更高。
本研究旨在评估采用CELT技术进行唇部填充后的患者满意度，并将其与传统脂肪制备方法（如沉淀法和过滤法）进行比较。该研究还试图评估其他变量（包括性别、年龄和脂肪注射量）对满意度结果的影响。
对接受自体脂肪移植唇部填充的患者进行回顾性病历审查。使用FACE-Q问卷测量满意度，重点关注与唇部相关的各个方面，如形状、丰满度以及嘴唇与面部的适配程度。该研究比较了CELT方法与沉淀/过滤联合技术的满意度结果。采用Kruskal-Wallis检验和Pearson相关性进行统计分析，以评估制备方法、注射量和患者人口统计学特征的影响。
与沉淀法和过滤法相比，CELT方法始终产生更高的满意度（所有项目p < 0.001）。接受CELT治疗的患者报告说，嘴唇形状、下唇丰满度和丘比特弓有更大改善。性别和年龄也是重要因素，男性在与微笑相关的方面满意度更高，而女性对唇部样式更满意。老年患者报告说，他们的嘴唇与面部的适配程度有更大改善，而较高的注射量与唇部丰满度和外观呈正相关。
与传统脂肪制备方法相比，CELT脂肪移植技术显著提高了唇部填充的患者满意度。CELT更高的脂肪保留率和更自然的效果使其成为唇部填充的更优选择。然而，需要进一步纳入客观体积测量的研究来验证这些发现。
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