Cardoso Jefferson Freire, do Valle Caio, Neppelenbroek Karin Hermana, Oliveira Valarelli Thais Marchini, Sforza Chiarella, Soares Simone
Department of Prosthodontics and Periodontology, Bauru School of Dentistry, University of São Paulo, Alameda Dr. Octávio Pinheiro Brisolla, 9-75, Bauru, SP, 17012-901, Brazil.
Instituto de Ensino Odontológico, Rua Guilherme de Almeida, 4-5, Bauru, SP, Brazil.
Aesthetic Plast Surg. 2025 Feb;49(3):875-884. doi: 10.1007/s00266-024-04410-6. Epub 2024 Sep 23.
The aim of this study was to evaluate changes in lip metrics before and after facial rejuvenation treatment with hyaluronic acid-based fillers and to compare them with those of a control group using stereophotogrammetry (3D).
This study included 63 Caucasian women divided into Group C (<30 years, n=30) and Group H (>30 years, n=33), which was further divided into before (HT0) and after (HT1) lip augmentation with hyaluronic acid (HA). Eleven anthropometric landmarks were identified for linear, angular, and surface area measurements. Three photos were captured in Group C, while Group H had photos taken at T0 and T1. Statistical analysis was conducted using the Shapiro-Wilk test to evaluate normality, the Kruskal-Wallis test and one-way ANOVA. Tukey's post hoc and pairwise comparison tests were performed to analyze differences between variables (P value < 0.05).
There were significant differences between lip width (ChR-ChL) and philtrum width (CphR-CphL) (P<.001). The total heights of the upper (Ls-Li) and lower vermilion lips (Sto-Li) increased, and the heights of the upper (Sn-Ls) and lower (Li-Sl) cutaneous lips decreased. The angles related to the philtrum (ChR-CphR-Ls, P<.001; ChL-CphL-Ls, P<.001) and nasolabial angle (Prn-Sn-Ls) (P<.001) exhibited significant differences. The surface areas of the upper, lower, and total vermilion lip showed significant differences (P<.001). Tukey's test indicated no significant differences in surface area after lip augmentation between the HT1 and C groups.
Analysis of lip morphology after a filler procedure revealed a reversal of age-related changes, with increases in vermilion lip height and surface area comparable to those of younger individuals.
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本研究旨在评估使用透明质酸填充剂进行面部年轻化治疗前后唇部指标的变化,并通过立体摄影测量法(3D)将其与对照组进行比较。
本研究纳入63名白种女性,分为C组(<30岁,n = 30)和H组(>30岁,n = 33),H组又进一步分为透明质酸(HA)丰唇前(HT0)和丰唇后(HT1)。确定了11个人体测量标志点用于线性、角度和表面积测量。C组拍摄3张照片,而H组在T0和T1时拍照。使用夏皮罗-威尔克检验评估正态性,采用克鲁斯卡尔-沃利斯检验和单因素方差分析进行统计分析。进行Tukey事后检验和成对比较检验以分析变量之间的差异(P值<0.05)。
唇宽(ChR-ChL)和人中宽(CphR-CphL)之间存在显著差异(P<0.001)。上唇(Ls-Li)和下唇朱红色部分(Sto-Li)的总高度增加,而上唇(Sn-Ls)和下唇(Li-Sl)皮肤部分的高度降低。与人中相关的角度(ChR-CphR-Ls,P<0.001;ChL-CphL-Ls,P<0.001)和鼻唇角(Prn-Sn-Ls)(P<0.001)存在显著差异。上唇、下唇和朱红色部分的总面积显示出显著差异(P<0.001)。Tukey检验表明HT1组和C组在丰唇后表面积无显著差异。
填充术后唇部形态分析显示与年龄相关的变化发生逆转,朱红色部分的高度和表面积增加,与年轻个体相当。
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